Nationwide surveillance of bacterial pathogens from patients with acute uncomplicated cystitis conducted by the Japanese surveillance committee during 2009 and 2010: antimicrobial susceptibility of Escherichia coli and
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- 作者：Hiroshi Hayami (1) (3)
Satoshi Takahashi (1) (4)
Kiyohito Ishikawa (1) (7)
Mitsuru Yasuda (1) (8)
Shingo Yamamoto (1) (10)
Shinya Uehara (1) (11)
Ryoichi Hamasuna (1) (13)
Tetsuro Matsumoto (1) (13)
Shinichi Minamitani (1)
Akira Watanabe (1)
Aikichi Iwamoto (1)
Kyoichi Totsuka (1)
Junichi Kadota (1)
Keisuke Sunakawa (1)
Junko Sato (1)
Hideaki Hanaki (2)
Taiji Tsukamoto (4)
Hiroshi Kiyota (6)
Shin Egawa (5)
Kazushi Tanaka (9)
Soichi Arakawa (9)
Masato Fujisawa (9)
Hiromi Kumon (11)
Kanao Kobayashi (12)
Akio Matsubara (12)
Seiji Naito (14)
Katsunori Tatsugami (14)
Takamasa Yamaguchi (15)
Shin Ito (16)
Mototsugu Kanokogi (17)
Harunori Narita (18)
Hiromi Kawano (19)
Takahide Hosobe (20)
Kazuo Takayama (21)
Toru Sumii (22)
Akira Fujii (23)
Takashi Sato (24)
Takamine Yamauchi (25)
Masanobu Izumitani (26)
Hirofumi Chokyu (27)
Hideari Ihara (28)
Kikuo Akiyama (29)
Masaru Yoshioka (30)
Satoshi Uno (31)
Koichi Monden (32)
Motonori Kano (33)
Shinichi Kaji (34)
Shuichi Kawai (35)
Kenji Ito (36)
Hisato Inatomi (37)
Hirofumi Nishimura (38)
Toshihiro Ikuyama (39)
Shohei Nishi (40)
Koichi Takahashi (41)
Yukihiro Kawano (42)
Satoshi Ishihara (43)
Kengo Tsuneyoshi (44)
Shinji Matsushita (45)
Takashi Yamane (46)
Takaoki Hirose (47)
Shigeru Fujihiro (48)
Katsuhisa Endo (49)
Yasuhiko Oka (50)
Koh Takeyama (51)
Takahiro Kimura (5)
Tetsuji Uemura (52) - 关键词：Surveillance ; Susceptibility ; Resistance ; Acute uncomplicated cystitis
- 刊名：Journal of Infection and Chemotherapy
- 出版年：2013
- 出版时间：June 2013
- 年：2013
- 卷：19
- 期：3
- 页码：393-403
- 全文大小：300KB
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3. Ishikawa K, Matsumoto T, Yasuda M, Uehara S, Muratani T, Yagisawa M, et al. The nationwide study of bacterial pathogens associated with urinary tract infections conducted by the Japanese Society of Chemotherapy. J Infect Chemother. 2011;17:126-8. CrossRef
4. Matsumoto T, Hamasuna R, Ishikawa K, Takahashi S, Yasuda M, Hayami H, et al. Nationwide survey of antibacterial activity against clinical isolates from urinary tract infections in Japan (2008). Int J Antimicrob Agents. 2011;37:210-. CrossRef
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6. Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard. 7th ed. Document M7-A7. Wayne: CLSI; 2006.
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8. Clinical and Laboratory Standards Institute. Methods for antimicrobial dilution and disk susceptibility testing of infrequently isolated or fastidious bacteria; approved guideline. Document M45-A. Wayne: CLSI; 2006.
9. Hanaki H, Kubo R, Nakano T, Kurihara M, Sunagawa K. Characterization of HMRZ-86: a novel chromogenic cephalosporin for the detection of extended-spectrum beta-lactamases. J Antimicrob Chemother. 2004;53:888-. CrossRef
10. Colodner R, Reznik B, Gal V, Yamazaki H, Hanaki H, Kubo R. Evaluation of a novel kit for the rapid detection of extended-spectrum beta-lactamases. Eur J Clin Microbiol Infect Dis. 2006;25:49-1. CrossRef
11. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; eighteenth informational supplement. Document M100-S18. Wayne: CLSI; 2008.
12. Foxman B. Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. Am J Med. 2002;113:5S-3S. CrossRef
13. Kahlmeter G. An international survey of the antimicrobial susceptibility of pathogens from uncomplicated urinary tract infections: the ECO.SENS Project. J Antimicrob Chemother. 2003;51:69-6. CrossRef
14. Schito GC, Naber KG, Botto H, Palou J, Mazzei T, Gualco L, et al. The ARESC study: an international survey on the antimicrobial resistance of pathogens involved in uncomplicated urinary tract infections. Int J Antimicrob Agents. 2009;34:407-3. CrossRef
15. Shigemura K, Tanaka K, Adachi M, Yamashita M, Arakawa S, Fujisawa M. Chronological change of antibiotic use and antibiotic resistance in / Escherichia coli causing urinary tract infections. J Infect Chemother. 2011;17:646-1. CrossRef
16. Acar CF, Goldstein FW. Trends in bacterial resistance to fluoroquinolones. Clin Infect Dis. 1997;24:S67-3. CrossRef
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19. Kahlmeter G, Poulsen HO. Antimicrobial susceptibility of / Escherichia coli from community-acquired urinary tract infections in Europe: the ECO.SENS study revisited. Int J Antimicrob Agents. 2012;39(1):45-1. CrossRef
20. Raz R, Colodner R, Kunin CM. Who are you-em class="a-plus-plus">Staphylococcus saprophyticus? Clin Infect Dis. 2005;40:896-. CrossRef
21. Killgore KM, March KL, Gugleilmo BJ. Risk factors for community-acquired ciprofloxacin-resistant / Escherichia coli urinary tract infection. Ann Pharmacother. 2004;38:1148-2. CrossRef
22. Kanda H, Kurosaka Y, Fujikawa K, Chiba M, Yamachika S, Okumura R, et al. In vitro and in vivo antibacterial activity of sitafloxacin. Jpn J Chemother. 2008;56:1-7.
23. Yamamoto S, Higuchi Y, Nojima M. Current therapy of acute uncomplicated cystitis. Int J Urol. 2010;17:450-. CrossRef
24. Ishikawa K, Hayakawa S, Miyakawa S, Kusaka M, Shiroki R, Hoshinaga K. Survey of the susceptibility of urinary isolates to antibacterial agents in 2003. J Infect Chemother. 2005;11:44-. CrossRef
25. Alekshun MN, Levy SB. Molecular mechanisms of antibacterial multidrug resistance. Cell. 2007;128:1037-0. CrossRef
26. Rupp ME, Soper DE, Archer GL. Colonization of the female genital tract with / Staphylococcus saprophyticus. J Clin Microbiol. 1992;30:2975-.
27. Latham RH, Running K, Stamm WE. Urinary tract infections in young adult women caused by / Staphylococcus saprophyticus. JAMA. 1983;250:3063-. CrossRef
28. Jellheden B, Norrby RS, Sandberg T. Symptomatic urinary tract infection in women in primary health care: bacteriological, clinical and diagnostic aspects in relation to host response to infection. Scand J Prim Health Care. 1996;14:122-. CrossRef
29. Saginur R, Nicolle LE. Single-dose compared with 3-day norfloxacin treatment of uncomplicated urinary tract infection in women. Canadian Infectious Diseases Society Clinical Trials Study Group. Arch Intern Med. 1992;152:1233-. CrossRef - 作者单位：Hiroshi Hayami (1) (3)
Satoshi Takahashi (1) (4)
Kiyohito Ishikawa (1) (7)
Mitsuru Yasuda (1) (8)
Shingo Yamamoto (1) (10)
Shinya Uehara (1) (11)
Ryoichi Hamasuna (1) (13)
Tetsuro Matsumoto (1) (13)
Shinichi Minamitani (1)
Akira Watanabe (1)
Aikichi Iwamoto (1)
Kyoichi Totsuka (1)
Junichi Kadota (1)
Keisuke Sunakawa (1)
Junko Sato (1)
Hideaki Hanaki (2)
Taiji Tsukamoto (4)
Hiroshi Kiyota (6)
Shin Egawa (5)
Kazushi Tanaka (9)
Soichi Arakawa (9)
Masato Fujisawa (9)
Hiromi Kumon (11)
Kanao Kobayashi (12)
Akio Matsubara (12)
Seiji Naito (14)
Katsunori Tatsugami (14)
Takamasa Yamaguchi (15)
Shin Ito (16)
Mototsugu Kanokogi (17)
Harunori Narita (18)
Hiromi Kawano (19)
Takahide Hosobe (20)
Kazuo Takayama (21)
Toru Sumii (22)
Akira Fujii (23)
Takashi Sato (24)
Takamine Yamauchi (25)
Masanobu Izumitani (26)
Hirofumi Chokyu (27)
Hideari Ihara (28)
Kikuo Akiyama (29)
Masaru Yoshioka (30)
Satoshi Uno (31)
Koichi Monden (32)
Motonori Kano (33)
Shinichi Kaji (34)
Shuichi Kawai (35)
Kenji Ito (36)
Hisato Inatomi (37)
Hirofumi Nishimura (38)
Toshihiro Ikuyama (39)
Shohei Nishi (40)
Koichi Takahashi (41)
Yukihiro Kawano (42)
Satoshi Ishihara (43)
Kengo Tsuneyoshi (44)
Shinji Matsushita (45)
Takashi Yamane (46)
Takaoki Hirose (47)
Shigeru Fujihiro (48)
Katsuhisa Endo (49)
Yasuhiko Oka (50)
Koh Takeyama (51)
Takahiro Kimura (5)
Tetsuji Uemura (52)
1. Urogenital sub-committee and the Surveillance Committee of Japanese Society of Chemotherapy (JCS), The Japanese Association for Infectious Diseases (JAID) and The Japanese Society for Clinical Microbiology (JSCM), Tokyo, Japan
3. Blood Purification Center, Kagoshima University Hospital, 8-35-1 Sakuragaoka, Kagoshima, 890-8520, Japan
4. Department of Urology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan
7. Department of Urology, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan
8. Department of Urology, Graduate School of Medicine, Gifu University, Gifu, Japan
10. Department of Urology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan
11. Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
13. Department of Urology, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
2. The Kitasato Institute, Tokyo, Japan
6. Department of Urology, The Jikei University Katsushika Medical Center, Tokyo, Japan
5. Department of Urology, The Jikei University School of Medicine, Tokyo, Japan
9. Division of Urology, Department of Surgery Related Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
12. Department of Urology, Hiroshima University Institute of Biomedical and Health Sciences, Hiroshima, Japan
14. Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
15. Yamaguchi Dermatology and Urology Clinic, Fukuoka, Japan
16. iClinic, Sendai, Miyagi, Japan
17. Kanokogi Clinic, Nishinomiya, Hyogo, Japan
18. Narita Clinic, Nagoya, Aichi, Japan
19. Kawano Urologic and Dermatologic Clinic, Fukuoka, Japan
20. Hosobe Clinic, Tokyo, Japan
21. Department of Urology, Takayama Hospital, Fukuoka, Japan
22. Sumii Clinic, Hiroshima, Japan
23. Nippon Steel Hirohata Hospital, Kobe, Hyogo, Japan
24. Nissin Urological Clinic, Hokkaido, Japan
25. Yamauchi Urological Clinic, Nagoya, Aichi, Japan
26. Izumitani Fureai Clinic, Nagoya, Aichi, Japan
27. Chokyu Tenma Clinic, Kobe, Hyogo, Japan
28. Ihara Clinic, Kobe, Hyogo, Japan
29. Akiyama Urology Clinic, Nishinomiya, Hyogo, Japan
30. Yoshioka Urology Clinic, Nishinomiya, Hyogo, Japan
31. Hirajima Clinic, Okayama, Japan
32. Araki Urological Clinic, Okayama, Japan
33. Department of Urology, Kano Hospital, Fukuoka, Japan
34. Kaji Clinic, Fukuoka, Japan
35. Kawai Urology Clinic, Fukuoka, Japan
36. Ito Urology Clinic, Fukuoka, Japan
37. Munakata Suikokai General Hospital, Fukuoka, Japan
38. Nishimura Urology Clinic, Fukuoka, Japan
39. Uenoharu Clinic, Fukuoka, Japan
40. Nishi Urology and Dermatology Clinic, Fukuoka, Japan
41. Fukuoka Shin Mizumaki Hospital, Fukuoka, Japan
42. Izumi General Center, Kagoshima, Japan
43. Kizawa Memorial Hospital, Gifu, Japan
44. Ibusuki National Hospital, Kagoshima, Japan
45. Kagoshima Prefectural Ohshima Hospital, Kagoshima, Japan
46. Kimotsuki-gun Medical Associated Hospital, Kagoshima, Japan
47. Hokkaido Social Insurance Hospital, Hokkaido, Japan
48. Department of Urology, Japanese Red Cross Gifu Hospital, Gifu, Japan
49. Department of Urology, JR Tokyo General Hospital, Tokyo, Japan
50. Kakogawa City Hospital, Kakogawa, Hyogo, Japan
51. Department of Urology, National Hospital Organization Hakodate National Hospital, Hokkaido, Japan
52. Remmedi Kitakyushu Nephro Clinic, Fukuoka, Japan - ISSN：1437-7780
文摘
The Japanese surveillance committee conducted the first nationwide surveillance of antimicrobial susceptibility patterns of uropathogens responsible for female acute uncomplicated cystitis at 43 hospitals throughout Japan from April 2009 to November 2010. In this study, the causative bacteria (Escherichia coli and Staphylococcus saprophyticus) and their susceptibility to various antimicrobial agents were investigated by isolation and culturing of bacteria from urine samples. In total, 387 strains were isolated from 461 patients, including E. coli (n?=?301, 77.8?%), S. saprophyticus (n?=?20, 5.2?%), Klebsiella pneumoniae (n?=?13, 3.4?%), and Enterococcus faecalis (n?=?11, 2.8?%). S. saprophyticus was significantly more common in premenopausal women (P?=?0.00095). The minimum inhibitory concentrations of 19 antibacterial agents used for these strains were determined according to the Clinical and Laboratory Standards Institute manual. At least 87?% of E. coli isolates showed susceptibility to fluoroquinolones and cephalosporins, and 100?% of S. saprophyticus isolates showed susceptibility to fluoroquinolones and aminoglycosides. The proportions of fluoroquinolone-resistant E. coli strains and extended-spectrum β-lactamase (ESBL)-producing E. coli strains were 13.3?% and 4.7?%, respectively. It is important to confirm the susceptibility of causative bacteria for optimal antimicrobial therapy, and empiric antimicrobial agents should be selected by considering patient characteristics and other factors. However, the number of isolates of fluoroquinolone-resistant or ESBL-producing strains in gram-negative bacilli may be increasing in patients with urinary tract infections (UTIs) in Japan. Therefore, these data present important information for the proper treatment of UTIs and will serve as a useful reference for future surveillance studies.