Enhancement of furan aldehydes conversion in Zymomonas mobilis by elevating dehydrogenase activity and cofactor regeneration
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- 作者：Xia Wang ; Qiuqiang Gao ; Jie Bao
- 关键词：Zymomonas mobilis ; Furfural ; 5 ; Hydroxymethylfurfural (HMF) ; Reduction ; Alcohol dehydrogenase ; Transhydrogenase
- 刊名：Biotechnology for Biofuels
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：10
- 期：1
- 全文大小：1161KB
- 刊物类别：Chemistry and Materials Science
- 刊物主题：Biotechnology; Plant Breeding/Biotechnology; Environmental Engineering/Biotechnology; Renewable and Green Energy; Renewable and Green Energy; Microbiology;
- 出版者：BioMed Central
- ISSN：1754-6834
- 卷排序：10
文摘
BackgroundFurfural and 5-hydroxymethylfurfural (HMF) are the two major furan aldehyde inhibitors generated from lignocellulose dilute acid pretreatment which significantly inhibit subsequent microbial cell growth and ethanol fermentation. Zymomonas mobilis is an important strain for cellulosic ethanol fermentation but can be severely inhibited by furfural and (or) HMF. Previous study showed that Z. mobilis contains its native oxidoreductases to catalyze the conversion of furfural and HMF, but the corresponding genes have not been identified.