Identification of QTLs associated with haze active proteins in barley

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• 作者：Lingzhen Ye ; Yuqing Huang ; Hongliang Hu ; Fei Dai ; Guoping Zhang
• 关键词：Barley ; Beer ; Haze active protein ; Quantitative trait locus (QTL)
• 刊名：Euphytica
• 出版年：2015
• 出版时间：October 2015
• 年：2015
• 卷：205
• 期：3
• 页码：799-807
• 全文大小：969 KB
• 参考文献：Asano K, Shinagawa K, Hashimoto N (1982) Characterization of haze-forming proteins of beer and their roles in chill haze formation. J Am Soc Brew Chem 40:147鈥?54
  Cai SG, Yu G, Chen XH, Huang YC, Jiang XG, Zhang GP, Jin XL (2013) Grain protein content variation and its association analysis in barley. BMC Plant Biol 13:35鈥?5PubMed Central CrossRef PubMed
  Chapon L (1993) Nephelometry as a method for studying the relations between polyphenols and proteins. J Inst Brew 99:49鈥?6CrossRef
  Dai F, Qiu L, Ye LZ, Wu DZ, Zhou MX, Zhang GP (2011) Identification of a phytase gene in barley (Hordeum vulgare L.). PLoS One 6:e18829. doi:10.鈥?371/鈥媕ournal.鈥媝one.鈥?018829 PubMed Central CrossRef PubMed
  Doerge RW (2002) Mapping and analysis of quantitative trait loci in experimental populations. Nat Rev Genet 3:43鈥?2CrossRef PubMed
  Evans DE, Robinson LH, Sheehan MC, Tolhurst RL, Hill A, Skerritt JS, Barr AR (2003) Application of immunological methods to differentiate between foam-positive and haze-active proteins originating from malt. J Am Soc Brew Chem 61:55鈥?2
  Fukuda K, Saito W, Arai S, Aida Y (1999) Production of a novel proanthocyanidin-free barley line with high quality. J Inst Brew 105:179鈥?83CrossRef
  Garvin DF, Miller-Garvin JE, Viccars EA, Jacobsen JV, Brown AHD (1998) Identification of molecular markers linked to ant28-484, a mutation that eliminates proanthocyanidin production in barley seeds. Crop Sci 38:1250鈥?255CrossRef
  Hayes PM, Liu BH, Knapp SJ, Chen F, Jones B, Blake T, Franckowiak J, Rasmusson D, Sorrells M, Ullrich SE, Wesenberg D, Kleinhofs A (1993) Quantitative trait locus effects and environmental interaction in a sample of north-American barley germplasm. Theor Appl Genet 87:392鈥?01CrossRef PubMed
  Iimure T, Nankaku N, Watanabe-Sugimoto M, Hirota N, Zhou TS, Kihara M, Hayashi K, Ito K, Sato K (2009) Identification of novel haze-active beer proteins by proteome analysis. J Cereal Sci 49:141鈥?47CrossRef
  Jin B, Li L, Li B, Liu BG, Liu GQ, Zhu YK (2009) Proteomics study of silica eluent proteins in beer. J Am Soc Brew Chem 67:183鈥?88
  Leiper KA, Stewart GG, McKeown IP (2003) Beer polypeptides and silica gel鈥擯art I. Polypeptides involved in haze formation. J Inst Brew 109:57鈥?2CrossRef
  Li CD, Tarr A, Lance RCM, Harasymow S, Uhlmann J, Westcot S, Young KJ, Grime CR, Cakir M, Broughton S, Appelsa R (2003) A major QTL controlling seed dormancy and pre-harvest sprouting/grain alpha-amylase in two-rowed barley (Hordeum vulgare L.). Aust J Agric Res 54:1303鈥?313CrossRef
  Li H, Vaillancourt R, Mendham N, Zhou M (2008) Comparative mapping of quantitative trait loci associated with waterlogging tolerance in barley (Hordeum vulgare L.). BMC Genom 9:401CrossRef
  Li CD, Cakir M, Lance R (2010) Genetic improvement of malting quality through conventional breeding and marker-assisted selection. In: Zhang GP, Li CD (eds) Genetics and improvement of barley malt quality, 1st edn. Springer, Berlin/Heidelberg, pp 260鈥?92
  Marquez-Cedillo LA, Hayes PM, Jones BL, Kleinhofs A, Legge WG, Rossnagel BG, Sato K, Ullrich E, Wesenberg DM, Barley NA (2000) QTL analysis of malting quality in barley based on the doubled-haploid progeny of two elite North American varieties representing different germplasm groups. Theor Appl Genet 101:173鈥?84CrossRef
  Mather D, Tinker N, LaBerge D, Edney M, Jones B, Rossnagel B, Legge W, Briggs K, Irvine R, Falk D (1997) Regions of the genome that affect grain and malt quality in a North American two-row barley cross. Crop Sci 37:544鈥?54CrossRef
  Mayer KFX, Waugh R, Langridge P, Close TJ, Wise RP, Graner A, Matsumoto T, Sato K, Schulman A, Muehlbauer GJ, Stein N, Ariyadasa R, Schulte D, Poursarebani N, Zhou RN, Steuernagel B, Mascher M, Scholz U, Shi BJ, Langridge P, Madishetty K, Svensson JT, Bhat P, Moscou M, Resnik J, Close TJ, Muehlbauer GJ, Hedley P, Liu H, Morris J, Waugh R, Frenkel Z, Korol A, Berges H, Graner A, Stein N, Steuernagel B, Taudien S, Groth M, Felder M, Platzer M, Brown JWS, Schulman A, Platzer M, Fincher GB, Muehlbauer GJ, Sato K, Taudien S, Sampath D, Swarbreck D, Scalabrin S, Zuccolo A, Vendramin V, Morgante M, Mayer KFX, Schulman A, Conso IBGS (2012) A physical, genetic and functional sequence assembly of the barley genome. Nature 491:711鈥?16PubMed
  Panozzo JF, Eckermann PJ, Mather DE, Moody DB, Black CK, Collins HM, Barr AR, Lim P, Cullis BR (2007) QTL analysis of malting quality traits in two barley populations. Aust J Agric Res 58:858鈥?66CrossRef
  Robinson LH, Healy P, Stewart DC, Eglinton JK, Ford CM, Evans DE (2007a) The identification of a barley haze active protein that influences beer haze stability: the genetic basis of a barley malt haze active protein. J Cereal Sci 45:335鈥?42CrossRef
  Robinson LH, Juttner J, Milligan A, Lahnstein J, Eglinton JK, Evans DE (2007b) The identification of a barley haze active protein that influences beer haze stability: cloning and characterisation of the barley SE protein as a barley trypsin inhibitor of the chloroform/methanol type. J Cereal Sci 45:343鈥?52CrossRef
  Shewry PR, Tatham AS, Halford NG (1999) Prolamin storage proteins. In: Shewry PR, Casey R (eds) Seed proteins. Springer, Netherlands, pp 11鈥?8CrossRef
  Siebert KJ (1999) Effects of protein-polyphenol interactions on beverage haze, stabilization, and analysis. J Agric Food Chem 47:353鈥?62CrossRef PubMed
  Siebert KJ, Carrasco A, Lynn PY (1996) Formation of protein-polyphenol haze in beverages. J Agric Food Chem 44:1997鈥?005CrossRef
  Siebert KJ, Lynn PY, Clark DF, Hatfield GR (2005) Comparison of methods for assessing colloidal stability of beer. Master Brew Assoc Am 42:7鈥?2
  Stewart DC, Hawthorne D, Evans DE (1998) Cold sterile filtration: a small scale filtration test and investigation of membrane plugging. J Inst Brew 104:321鈥?26CrossRef
  Szucs P, Blake VC, Bhat PR, Chao SAM, Close TJ, Cuesta-Marcos A, Muehlbauer GJ, Ramsay L, Waugh R, Hayes PM (2009) An integrated resource for barley linkage map and malting quality QTL alignment. Plant Genome-Us 2:134鈥?40CrossRef
  Thompson CC, Forward E (1969) European Brewery convention: haze and foam group. Towards the chemical prediction of shelf life. J Inst Brew 75:37鈥?2CrossRef
  Van Ooijen J (2004) MapQTL庐 5. Software for the mapping of quantitative trait loci in experimental populations. Kyazma BV, Wageningen
  Wang Y, Gupta S, Wallwork H, Zhang X-Q, Zhou G, Broughton S, Loughman R, Lance R, Wu D, Shu X, Li C (2014) Combination of seedling and adult plant resistance to leaf scald for stable resistance in barley. Mol Breed 34:2081鈥?089CrossRef
  Ye LZ, Dai F, Qiu L, Sun DF, Zhang GP (2011) Allelic diversity of a beer haze active protein gene in cultivated and Tibetan wild barley and development of allelic specific markers. J Agric Food Chem 59:7218鈥?223CrossRef PubMed
  Ye LZ, Huang L, Huang YQ, Wu DZ, Hu HL, Li CD, Zhang GP (2014) Haze activity of different barley trypsin inhibitors of the chloroform/methanol type (BTI-CMe). Food Chem 165:175鈥?80CrossRef PubMed
  Zale JM, Clancy JA, Ullrich SE, Jones BL, Hayes PM (2000) Summary of barley malting quality QTLs mapped in various populations. Barley Genet Newsl 30:44鈥?4
  
• 作者单位：Lingzhen Ye (1)
  Yuqing Huang (1)
  Hongliang Hu (1)
  Fei Dai (1)
  Guoping Zhang (1)
  
  1. Agronomy Department, Zhejiang University, Hangzhou, 310058, China
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Plant Physiology
  Plant Sciences
  Ecology
  
• 出版者：Springer Netherlands
• ISSN：1573-5060

文摘

Haze formation in beer is a trait closely related to beer quality and it is largely affected by the haze active proteins (HAPs) in barley (Hordeum vulgare L.). Up to date, little is known about the genetics of HAPs and relevant genes. In this study, we obtained the beer samples from a Franklin/Yerong double haploid (DH) population and the two parents using micro-malting and micro-brewing, and determined tannin-related HAPs. It was found that there was a wide difference in HAPs among all lines of the DH population, and Yerong had a higher HAPs content than Franklin. Quantitative trait locus (QTL) analysis identified five QTLs associated with HAPs in beer, being located on chromosomes 1HS, 5HL and 6HS, respectively. The loci QHAP1.FrYe-1H and QHAP2.FrYe-1H were overlapped in the short arm of chromosome 1H, and they controlled HAP1 and HAP2, respectively. Moreover, the candidate genes were also predicted based on published whole barley genome sequence and corresponding gene annotations. Keywords Barley Beer Haze active protein Quantitative trait locus (QTL)