An untargeted metabolomics method for archived newborn dried blood spots in epidemiologic studies
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- 作者：Lauren Petrick ; William Edmands ; Courtney Schiffman ; Hasmik Grigoryan…
- 关键词：Dried blood spots ; Small molecules ; LC ; HRMS ; Hematocrit ; Metabolome
- 刊名：Metabolomics
- 出版年：2017
- 出版时间：March 2017
- 年：2017
- 卷：13
- 期：3
- 全文大小：
- 刊物主题：Biochemistry, general; Molecular Medicine; Cell Biology; Developmental Biology; Biomedicine, general;
- 出版者：Springer US
- ISSN：1573-3890
- 卷排序：13
文摘
IntroductionFor pediatric diseases like childhood leukemia, a short latency period points to in-utero exposures as potentially important risk factors. Untargeted metabolomics of small molecules in archived newborn dried blood spots (DBS) offers an avenue for discovering early-life exposures that contribute to disease risks.