Survival in Resected Stage II Colorectal Cancer Is Dependent on Tumor Depth, Vascular Invasion, Postoperative CEA Level, and The Number of Examined Lymph Nodes
参考文献:1.Cancer registry annual report, Taiwan, R.O.C., 2011. Taipei: Ministry of Health and Welfare, the Executive Yuan, R.O.C., 2011. http://www.hpa.gov.tw/BHPNet/Web/Stat/StatisticsShow.aspx?No=201404160001 2.Shepherd NA, Baxter KJ, Love SB (1997) The prognostic importance of peritoneal involvement in colonic cancer: a prospective evaluation. Gastroenterology 112:1096–1102CrossRef PubMed 3.Ambiru S, Miyazaki M, Ito H et al (1998) Resection of hepatic and pulmonary metastases in patients with colorectal carcinoma. Cancer 82:274–278CrossRef PubMed 4.Michael JO, Megan EC, Richard MG et al (2008) Survival following recurrence in stage II and III colon cancer: findings from the ACCENT data set. J Clin Oncol 26:2336–2341CrossRef 5.Hwang CC, Chai HT, Chen HW et al (2011) S100B protein expressions as an independent predictor of early relapse in UICC stage II and III colon cancer patients after curative resection. Ann Surg Oncol 18:139–145CrossRef PubMed 6.Tsai HL, Yang IP, Lin CH et al (2013) Predictive value of vascular endothelial growth factor overexpression in early relapse of colorectal cancer patients after curative resection. Int J Colorectal Dis 28:415–424CrossRef PubMed 7.Sobin LH, Gospodarowicz MK, Wittekind C (2009) TNM Classification of malignant tumors, 7th edn. Wiley, New York, pp 100–105 8.Hamilton SR, Vogelstein B, Kudo S et al (2000) Carcinoma of the colon and rectum. In: Hamilton SR, Aaltonen LA (eds) World health organization classification of tumors, pathology and genetics. Tumors of the Digestive System, Lyon, pp 105–119 9.Tsai HL, Chu KS, Huang YH et al (2009) Predictive factors of early relapse in UICC stage I–III colorectal cancer patients after curative resection. J Surg Oncol 100:736–743CrossRef PubMed 10.Tsai HL, Yang IP, Huang CW et al (2013) Clinical significance of microRNA-148a in patients with early relapse of stage II and III colorectal cancer after curative resection. Transl Res 162:258–268CrossRef PubMed 11.Lipska L, Visokai V, Levy M et al (2007) Tumor markers in patients with relapse of colorectal carcinoma. Anticancer Res 27:1901–1906PubMed 12.Klaus D, William S, Frank O et al (2012) Absence of extramural venous invasion is an excellent predictor of metastasis-free survival in colorectal carcinoma stage II- a study using tangential tissue sectioning. J Clin Pathol 65:619–623CrossRef 13.Morris M, Platell C, deBoer B et al (2006) Population-based study of prognostic factors in stage II colonic cancer. Br J Surg 93:866–871CrossRef PubMed 14.Petersen VC, Baxter KJ, Love SB et al (2002) Identification of objective pathological prognostic determinants and models of prognosis in Dukes’ B colon cancer. Gut 51:65–69PubMedCentral CrossRef PubMed 15.Desolneux G, Burtin P, Lermite E et al (2010) Prognostic factors in node-negative colorectal cancer: a retrospective study from a prospective database. Int J Colorectal Dis 25:829–834CrossRef PubMed 16.Quirke P, Morris E (2007) Reporting colorectal cancer. Histopathology 50:103–112CrossRef PubMed 17.Khankhanian N, Mavligit GM, Russell WO et al (1977) Prognostic significance of vascular invasion in colorectal cancer of Dukes’ B class. Cancer 39:1195–1200CrossRef PubMed 18.Ishizuka D, Shirai Y, Sakai Y et al (2001) Colorectal carcinoma liver metastases: clinical significance of preoperative measurement of serum carcinoembryonic antigen and carbohydrate antigen 19-9 level. Int J Colorectal Dis 16:32–37CrossRef PubMed 19.Holubee L Jr, Topolcan O, Pikner R et al (2003) Criteria for the selection of referential groups in tumor marker statistical evaluation on the basis of a retrospective study. Anticancer Res 23:856–870 20.Chapman MA, Buckley D, Henson DB et al (1998) Preoperative carcinoembryonic antigen is related to tumor stage and long-term survival in colorectal cancer. Br J Cancer 78:1346–1349PubMedCentral CrossRef PubMed 21.Lin JK, Lin CC, Yang SH et al (2011) Early postoperative CEA level is a better prognostic indicator than is preoperative CEA level in predicting prognosis of patients with curable colorectal cancer. Int J Colorectal Dis 26:1135–1141CrossRef PubMed 22.Park YA, Lee KY, Kim NK et al (2006) Prognostic effect of perioperative change of serum carcinoembryonic antigen level: a useful tool for detection of systemic recurrence in rectal cancer. Ann Surg Oncol 13:645–650CrossRef PubMed 23.Wang JY, Lu CY, Chu KS et al (2007) Prognostic significance of pre- and postoperative serum carcinoembryonic antigen levels in patients with colorectal cancer. Eur Surg Res 39:245–250CrossRef PubMed 24.Hotta T, Takifuji K, Uchiyama K et al (2006) Potential predictors of survival after surgery for colorectal cancer patients with synchronous unresectable liver metastases. Oncol Rep 16:1369–1374PubMed 25.Yakabe T, Nakafusa Y, Sumi K et al (2010) Clinical significance of CEA and CA 19-9 in postoperative follow-up of colorectal cancer. Ann Surg Oncol 17:2349–2356CrossRef PubMed 26.McCall JL, Black RB, Rich CA et al (1994) The value of serum carcinoembryonic antigen in predicting recurrence disease following curative resection of colorectal cancer. Dis Colon Rectum 37:875–881CrossRef PubMed 27.Wang JY, Lu CY, Chu KS et al (2007) Prognostic significance of per- and post-operative serum carcinoembryonic antigen levels in patients with colorectal cancer. Eur Surg Res 39:245–250CrossRef PubMed 28.Tsai HL, Cheng KI, Lu CY et al (2008) Prognostic significance of depth of invasion, vascular invasion and numbers of lymph node retrievals in combination for patients with stage II colorectal cancer undergoing radical resection. J Surg Oncol 97:383–387CrossRef PubMed 29.Bilimoria KY, Stewart AK, Palis BE et al (2008) Adequacy and importance of lymph node evaluation for colon cancer in the elderly. J Am Coll Surg 206:247–254CrossRef PubMed 30.Vather R, Sammour T, Kahokehr A et al (2009) Lymph node evaluation and long-term survival in stage II and stage III colon cancer: a national study. Ann Surg Oncol 16:585–593CrossRef PubMed 31.Green FL, Page DL, Fleming ID et al (2001) AJCC cancer staging handbook, 6th edn. Springer, New York
1. Division of Gastroenterology and General Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan 2. Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan 3. Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan 4. Division of Colorectal Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan 5. Department of Emergency Medicine, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan 6. Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan 7. Division of Gastroenterology and General Surgery, Department of Surgery, Kaohsiung Medical University Hospital, and Center for Biomarkers and Biotech Drugs, Kaohsiung Medical University, No. 100, Tzyou 1st Road, 807, Kaohsiung, Taiwan
刊物类别:Medicine
刊物主题:Medicine & Public Health Surgery Abdominal Surgery Cardiac Surgery General Surgery Thoracic Surgery Vascular Surgery
出版者:Springer New York
ISSN:1432-2323
文摘
Background The aim of the present study was to determine which aspects of tumor histology influence postoperative early relapse and overall survival rates after radical resection of stage II colorectal cancer (CRC).