Glioma grading by microvascular permeability parameters derived from dynamic contrast-enhanced MRI and intratumoral susceptibility signal on susceptibility weighted imaging
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  • 作者:Xiaoguang Li ; Yongshan Zhu ; Houyi Kang ; Yulong Zhang ; Huaping Liang…
  • 关键词:Brain tumor ; Glioma ; Grading ; Dynamic contrast ; enhanced MRI ; Susceptibility weighted imaging ; Intratumoral susceptibility signal
  • 刊名:Cancer Imaging
  • 出版年:2015
  • 出版时间:December 2015
  • 年:2015
  • 卷:15
  • 期:1
  • 全文大小:2589KB
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  • 作者单位:Xiaoguang Li (1)
    Yongshan Zhu (2)
    Houyi Kang (1)
    Yulong Zhang (1)
    Huaping Liang (3)
    Sumei Wang (4)
    Weiguo Zhang (1) (3)

    1. Department of Radiology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, 400042, China
    2. Department of Radiology, Tianchang people鈥檚 hospital, Tianchang, Anhui, 239300, China
    3. State key laboratory of Trauma, Burns and Combined Injury, Institute of Surgery Research, Daping Hospital, Third Military Medical University, No. 10, Changjiang Zhilu, Da Ping, Yuzhong Distriction, Chongqing, 400042, China
    4. Division of Neuroradiology, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA19104, USA
  • 刊物类别:Imaging / Radiology; Cancer Research; Oncology;
  • 刊物主题:Imaging / Radiology; Cancer Research; Oncology;
  • 出版者:BioMed Central
  • ISSN:1470-7330
文摘
Background Dynamic contrast-enhanced MRI (DCE-MRI) estimates vascular permeability of brain tumors, and susceptibility-weighted imaging (SWI) may demonstrate tumor vascularity by intratumoral susceptibility signals (ITSS). This study assessed volume transfer constant (Ktrans) accuracy, the volume of extravascular extracellular space (EES) per unit volume of tissue (Ve) derived from DCE-MRI, and the degree of ITSS in glioma grading.

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