Antioxidant and antiproliferation activities of winter cereal crops before and after germination
详细信息    查看全文
  • 作者:Hyun Young Kim (3)
    Sang Hoon Lee (1)
    In Guk Hwang (2)
    Koan Sik Woo (3)
    Kee Jong Kim (4)
    Mi Ja Lee (4)
    Dae Joong Kim (5)
    Tae Jip Kim (1)
    Junsoo Lee (1)
    Heon Sang Jeong (1)
  • 关键词:wheat ; barley ; germination ; antioxidant activity ; anticancer
  • 刊名:Food Science and Biotechnology
  • 出版年:2013
  • 出版时间:February 2013
  • 年:2013
  • 卷:22
  • 期:1
  • 页码:181-186
  • 参考文献:1. Cheng HY, Lin TC, Yu KH, Yang CM, Lin CC. Antioxidant and free radical scavenging activities of / Terminalia chebula. Biol. Pharm. Bull. 26: 1331鈥?335 (2003) CrossRef
    2. Slater TF. Free-radical mechanisms in tissue injury. Biochem. J. 222: 1鈥?5 (1984)
    3. Halliwell B. Antioxidants and human disease: A general introduction. Nutr. Rev. 55: S44鈥揝52 (1997) CrossRef
    4. Bartold PM, Wiebkin OW, Thonard JC. The effect of oxygenderived free radicals on gingival proteoglycans and hyaluronic acid. J. Periodontal Res. 19: 390鈥?00 (1984) CrossRef
    5. Varani J, Fligiel SEG, Till GO, Kunkel RG, Ryan VS, Ward PA. Pulmonary endothelial cell killing by human neutrophils: Possible involvement of hydroxyl radical. Lab. Invest. 53: 656鈥?63 (1985)
    6. Adom K, Liu R. Antioxidant activity of grains. J. Agr. Food Chem. 50: 6182鈥?187 (2002) CrossRef
    7. Baublis A, Decker EA, Clydesdale FM. Antioxidant effects of aqueous extracts from wheat-based ready-to-eat breakfast cereals. Food Chem. 68: 1鈥? (2000) CrossRef
    8. Emmons CL, Peterson DM, Paul GL. Antioxidant capacity of oat ( / Avena sativa L.) extracts. 2. / In vitro antioxidant activity and contents of phenolic and tocol antioxidants. J. Agr. Food Chem. 47: 4894鈥?898 (1999) CrossRef
    9. Hahm TS, Park SJ, Martin LY. Effects of germination on chemical composition and functional properties of sesame ( / Sesamum indicum L.) seeds. Bioresource Technol. 100: 1643鈥?647 (2009) CrossRef
    10. Madhujith T, Shahidi F. Optimization of the extraction of antioxidative constituents of six barley cultivars and their antioxidant properties. J. Agr. Food Chem. 54: 8048鈥?057 (2006) CrossRef
    11. Bol铆var ACC, Luis CZ. Impact of germination on phenolic content and antioxidant activity of 13 edible seed species. Food Chem. 119: 1485鈥?490 (2010) CrossRef
    12. Liyana-Pathirana CM, Dexter J, Shahidi F. Antioxidant properties of wheat as affected by pearling. J. Agr. Food Chem. 54: 6177鈥?184 (2006) CrossRef
    13. Madhujith T, Shahidi F. Antioxidative and antiproliferative properties of selected barley ( / Hordeum vulgarae L.) cultivars and their potential for inhibition of low-density lipoprotein (LDL) cholesterol oxidation. J. Agr. Food Chem. 55: 5018鈥?024 (2007) CrossRef
    14. Singleton VL, Rossi JA Jr. Colorimetric of total phenolics with phosphomolybdic-phosphotungstic acid reagents. Am. J. Enol. Viticult. 16: 144鈥?58 (1965)
    15. Jia Z, Tang M, Wu J. The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals. Food Chem. 64: 555鈥?59 (1999) CrossRef
    16. Cheung LM, Cheung PCK, Ooi VEC. Antioxidant activity and total polyphenolics of edible mushroom extracts. Food Chem. 81: 249鈥?55 (2003) CrossRef
    17. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Bio. Med. 26: 1231鈥?237 (1999) CrossRef
    18. Forni LG, Mora-Arellano VO, Packer JE, Willson RL. Nitrogen dioxide and related free radicals: Electron-transfer reactions with organic compounds in solutions containing nitrite or nitrate. J. Chem. Soc. Pakistan 2: 1鈥? (1986)
    19. Lee YR, Woo KS, Kim JY, Son JR, Jeong HS. Antioxidant activities of ethanol extracts from germinated specialty rough rice. Food Sci. Biotechnol. 16: 765鈥?70 (2005)
    20. Sosulski F, Krygier K, Hogge L. Free, esterified, and insolublebound phenolic acids. 3. Composition of phenolic acids in cereal and potato flours. J. Agr. Food Chem. 30: 337鈥?40 (1982) CrossRef
    21. Cevallos-Casals BA, Cisneros-Zevallos L. Impact of germination on phenolic content and antioxidant activity of 13 edible seed species. Food Chem. 119: 1485鈥?490 (2010) CrossRef
    22. Lee YR, Kim JY, Woo KS, Hwang IG, Kim KH, Kim KJ, Kim JH, Jeong HS. Changes in the chemical and functional components of Korean rough rice before and after germination. Food Sci. Biotechnol. 16: 1006鈥?010 (2007)
    23. Lopez-Amoros ML, Hernandez T, Estrella I. Effect of germination on legume phenolic compounds and their antioxidant activity. J. Food Compos. Anal. 19: 277鈥?83 (2006) CrossRef
    24. Harborne JB, Williams CA. Advances in flavonoid research since 1992. Phytochemistry 55: 481鈥?04 (2000) CrossRef
    25. Duenas M, Hernandez T, Estrella I, Fernandez D. Germination as a process to increase the polyphenol content and antioxidant activity of lupin seeds ( / Lupinus angustifolius L.). Food Chem. 117: 599鈥?07 (2009) CrossRef
    26. Gutteridge JMC, Halliwell B. Free radicals and antioxidants in the year 2000: A historical look to the future. Ann. NY Acad. Sci. 899: 136鈥?47 (2000) CrossRef
    27. Craig WJ. Phytochemicals: Guardians of our health. J. Am. Diet. Assoc. 97: S199鈥揝204 (1997) CrossRef
  • 作者单位:Hyun Young Kim (3)
    Sang Hoon Lee (1)
    In Guk Hwang (2)
    Koan Sik Woo (3)
    Kee Jong Kim (4)
    Mi Ja Lee (4)
    Dae Joong Kim (5)
    Tae Jip Kim (1)
    Junsoo Lee (1)
    Heon Sang Jeong (1)

    3. Department of Functional Crop, National Institute of Crop Science, Miryang, Gyeongnam, 627-803, Korea
    1. Department of Food Science and Technology, Chungbuk National University, Cheongju, Chungbuk, 361-763, Korea
    2. Department of Agrofood Resources, National Academy of Agricultural Science, Suwon, Gyeonggi, 441-857, Korea
    4. Division of Rice and Winter Cereal Crop, National Institute of Crop Science, Iksan, Jeonbuk, 570-080, Korea
    5. College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, 361-763, Korea
  • ISSN:2092-6456
文摘
This study investigated the changes in antioxidant and antiproliferation activities of germinated winter cereal crops, including oats, barley, rye, and wheat, to develop functional materials. The highest total polyphenol content was found post-germination at 3.97 mg gallic acid equiv./g, which was 1.61-fold higher than the 2.46 mg gallic acid equiv./g in pre-germination barley. The flavonoid content was highly increased in wheat, which was 2.25-fold higher than 0.28 mg catechin equiv./g sample in pre-germination. The DPPH free radical scavenging activity (IC50) was the greatest in the post-germination barley at 1.67 mg/mL. The highest ascorbic acid equivalent antioxidant capacity (7.43 mg AA eq/g sample) was obtained from post-germination barley, while its pre-germination capacity was 5.44 mg AA eq/g sample. The post-germination oats ethanol extract had a higher antiproliferation effect on HepG2 and HCT-116 cell lines than the pre-germination extract. The cell viability of the HepG2 and HCT-116 cell lines exposed to the post-germination oats was 19.98 and 11.81% at 3.0 mg/mL, respectively.

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700