Randomized Controlled Trial of Hyalobarrier® Versus No Hyalobarrier® on the Ovulatory Status of Women with Periovarian Adhesions: A Pilot Study
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- 作者：Ying Cheong ; Sarah Bailey ; Jane Forbes
- 关键词：Adhesiolysis ; Fertility ; Hyalobarrier ; Ovary ; Adhesion prevention
- 刊名：Advances in Therapy
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：34
- 期：1
- 页码：199-206
- 全文大小：627KB
- 刊物主题：Internal Medicine; Oncology; Cardiology; Rheumatology; Endocrinology; Pharmacology/Toxicology;
- 出版者：Springer Healthcare
- ISSN：1865-8652
- 卷排序：34
文摘
IntroductionPeriadnexal adhesions are known to contribute to subfertility. The restoration of the tubo-ovarian anatomy is one the key principles in reproductive surgery, and this involves adhesiolysis. However, adhesion formation/reformation is very common after periovarian adhesiolysis. It is not known if the application of Hyalobarrier®, an anti-adhesion gel, around the adnexal region postsurgery influences ovulatory status. The study is a pilot randomized controlled trial (RCT) randomizing women into the application of Hyalobarrier® versus no Hyalobarrier® at the time of laparoscopy, where postsurgical ovulatory status and pregnancy rates were evaluated.