Octahedral titanium(IV) complexes with five novel hydroximic acid ligands: Synthesis, spectroscopic characterization, and in vitro activities on IMR-32 and CHO cell lines and ten bacterial strains
详细信息 查看全文
- 作者：Sheetal ; K. Nehra ; R. Kaushal ; S. Arora ; D. Kaur…
- 关键词：Titanium ; hydroxamic acid ; spectroscopy ; anticancer and antibacterial activity
- 刊名：Russian Journal of General Chemistry
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：86
- 期：1
- 页码：154-160
- 全文大小：236 KB
- 参考文献：1.Mishra, H., Parrill, A.L., and Williamson, J.S., Antimicrob. Agents Chemother., 2002, vol. 46, p. 2613. DOI: 10.1128/AAC.46.8.2613-2618.2002CrossRef
2.Muri, E.M.F., Nieto, M.J., Sindelar, R.D., and Williamson, J.S., Curr. Med. Chem., 2002, vol. 9, p. 1631.CrossRef
3.Leung, D., Abbenante, G., and Fairlie, D.P., J. Med. Chem., 2000, vol. 43, p 305. DOI: 10.1021/jm990412mCrossRef
4.Hidalgo, M. and Eckhardt, S.G., J. Nat. Cancer Inst., 2001, vol. 93, p. 178.CrossRef
5.Marks, P.A., Richon, V.M., and Rifkind, R.A., J. Nat. Cancer Inst., 2000, vol. 92, p.1210.CrossRef
6.Brammer, R., Buckels, J., and Bramhall, S., Int. J. Clin. Pract., 2000, vol. 54, p. 373.
7.Grant, S.K., Green, B.G., and Kozarich, J.W., Bioorg. Chem., 2001, vol. 29, p. 211.CrossRef
8.Apfel, C., Banner, D.W., Bur, D., Dietz, M., Hirata, T., Hubschwerlen, C., Locher, H., Page, M.G.P., Pirson, W., Rosse, G., and Specklin, J.-L., J. Med. Chem., 2000, vol. 43, p. 2324. DOI: 10.1021/jm000018kCrossRef
9.Schraml, J., Appl. Organomet. Chem., 2000, vol. 14, p. 604. DOI: 10.1002/1099-0739(200010)14:10<604:: AID-AOC45>3.0.CO;2-3CrossRef
10.Wang, G.-C., Lu, Y.-N., Xiao, J., Yu, L., Song, H.-B., Li, J.-S., Cui, J.-R., Wang, R.-Q., and Ran, F.-X., J. Organomet. Chem., 2005, vol. 690, p. 151.CrossRef
11.Schraml, J., Tkadlecova, M., Pataridis, S., Soukupova, L., Blechta, V., Roithova, J., and Exner, O., Magn. Reson. Chem., 2005, vol. 43, p. 535.CrossRef
12.Farkas, E., Enyedy, E.A., Micera, G., and Garribba, E., Polyhedron, 2000, vol. 19, p. 1727.CrossRef
13.Kostova, I., Recent Pat. Anti-Cancer Drug Discovery, 2006, vol. 1, p. 1.CrossRef
14.Melendez, E., Crit. Rev. Oncol./Hematol., 2002, vol. 42, p. 309.CrossRef
15.Lakhai, J.M.R., Bongard, D.V.D., Pluim, D., Beijnen, J.H., and Schellens, J.H.M., Clin. Cancer Res., 2004, vol. 10, p. 3717.CrossRef
16.Gabbiani, C., Casini, A., and Messori, L., Gold Bull., 2007, vol. 40, p. 73.CrossRef
17.Kruger, N., Kleeberg, U.R., Mroßs, K., Edler, L., Saß, G., and Hossfeld, D.K., Onkologie, 2000, vol. 23, p. 60.CrossRef
18.Shang, X., Cui, J., Wu, J., Pombeiro, A.J.L., and Li, Q., J. Inorg. Biochem., 2008, vol. 102, p. 901.CrossRef
19.Pettinari, C., Marchetti, F., Pettinari, R., Martini, D., Drozdov, A., and Troyanov, S., Inorg. Chim. Acta, 2001, vol. 325, p.103.CrossRef
20.Saad, E., Farina, Y., Baba, I., and Othman, H., Sains Malays., 2003, vol. 32, p. 79.
21.Zhu, Y., Chen, X., Wu, Z., Zheng, Y., Chen, Y., Tang, W., and Lu, T., Arch. Pharm. Res., 2012, vol. 35, p. 1723.CrossRef
22.Khan, N., Farina, Y., Mun, L.K., Raja, N.F., and Awang, N., J. Organomet. Chem., 2014, vol. 763, p. 26.CrossRef
23.Vogt, T.N.P., Pacco, A., Walrand, C.G., and Binnemans, K., J. Inorg. Biochem., 2005, vol. 99, p. 497.CrossRef
24.Tkac, P., Matteson, B., Bruso, J., and Paulenova, A., J. Radioanal. Nucl. Chem., 2008, vol. 277, p. 31.CrossRef
25.Ferrari, M., Fornasiero, M.C., and Isetta, A.M., J. Immunol. Methods, 1990, vol. 131, p. 165.CrossRef
26.Li, Q., Guedes da Silva, M.F.C., Jinghua, Z., and Pombeiro, A.J.L., J. Organomet. Chem., 2004, vol. 689, p. 4584.CrossRef
27.Pizarro, A.M., Habtemariam, A., and Sadler, P.J., Top. Organomet. Chem., 2008, vol. 32, p. 21.
28.Masoud, J.N., Kondejewski, L.H., Wheaton, L.C., and Hodges, R.S., J. Med. Chem., 2009, vol. 52, p. 2090.CrossRef
29.Moradell, S., Lorenzo, J., Rovira, A., Zutphen, V.S., Aviles, F.X., Moreno, V., Llorens, D.R., Martinez, M.A., Reedijk, J., and Llobet, A., J. Inorg. Biochem., 2004, vol. 98, p. 1933CrossRef
30.Chohan, Z.H., Supuran, C.T., and Scozzafava, A., J. Enzyme Inhib. Med. Chem., 2004, vol. 19, p. 79.CrossRef
31.Chohan Z.H., Hassan, M.U.I., Khan, K.M., and Supuran, C.T., J. Enzyme Inhib. Med. Chem., 2005, vol. 20, p. 183.CrossRef - 作者单位：Sheetal (1)
K. Nehra (2)
R. Kaushal (3)
S. Arora (4)
D. Kaur (4)
R. Kaushal (1)
1. Department of Chemistry, National Institute of Technology, Hamirpur, Himachal Pradesh, 177005, India
2. Department of Biotechnology, Deenbandhu Chhotu Ram University of Science and Technology, Murthal, 131039, Sonepat (Haryana), India
3. Department of Parasitology, PGIMER, Chandigarh, 160012, India
4. Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar, Punjab, 143005, India - 刊物类别：Chemistry and Materials Science
- 刊物主题：Chemistry
Chemistry
Russian Library of Science - 出版者：MAIK Nauka/Interperiodica distributed exclusively by Springer Science+Business Media LLC.
- ISSN：1608-3350
文摘
Complexes with the composition TiCl4L2 where L = benzohydroxamic acid, 2-hydroxybenzo-hydroxamic acid, acetohydroxamic acid, hydroxyurea, and N-hydroxy-N-phenylbenzamide have been synthesized by reaction of titanium tetrachloride with 2 equiv of the corresponding hydroxamic acids. The structure of these complexes has been studied by analytical and spectroscopic (FT-IR, UV-Vis, MS, 1H and 13C NMR) techniques. The free ligands and the complexes have been tested in vitro to evaluate their activities against IMR-32 (neuroblastoma) cancer cell line, CHO p-40 (Chinese hamster ovary) normal cells, and ten pathogenic bacterial strains.