Multiplatform metabolomic fingerprinting as a tool for understanding hypercholesterolemia in Wistar rats

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• 作者：Diana González-Peña ; Danuta Dudzik ; Clara Colina-Coca…
• 关键词：Atherosclerosis ; Global profiling ; High ; cholesterol diet ; Metabolomics ; Untargeted analysis
• 刊名：European Journal of Nutrition
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：55
• 期：3
• 页码：997-1010
• 全文大小：1,446 KB
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• 作者单位：Diana González-Peña (1)
  Danuta Dudzik (2)
  Clara Colina-Coca (1)
  Begoña de Ancos (1)
  Antonia García (2)
  Coral Barbas (2)
  Concepción Sánchez-Moreno (1)
  
  1. Institute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CSIC), José Antonio Novais 10, 28040, Madrid, Spain
  2. Center for Metabolomics and Bioanalysis (CEMBIO), Faculty of Pharmacy, San Pablo CEU University, Boadilla del Monte, 28668, Madrid, Spain
  
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Nutrition
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1436-6215

文摘

Purpose The aim was to investigate the impact of hypercholesterolemic diet on the metabolome of male Wistar rats by a multiplatform metabolomic fingerprinting.