Deferring surgical treatment of ambiguous genitalia into adolescence in girls with 21-hydroxylase deficiency: a feasibility study
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- 作者：Pierre Bougnères ; Claire Bouvattier…
- 关键词：21 ; hydroxylase deficiency ; Ambiguous genitalia ; Congenital adrenal hyperplasia ; Genital surgery
- 刊名：International Journal of Pediatric Endocrinology
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：2017
- 期：1
- 全文大小：914KB
- 刊物主题：Pediatrics; Endocrinology; Maternal and Child Health; Metabolic Diseases; Internal Medicine;
- 出版者：BioMed Central
- ISSN：1687-9856
- 卷排序：2017
文摘
BackgroundGenital surgery in Disorders of Sex Development (DSD) has been an area of debate over the past 20 years. Emerging scientific evidence in the late 1990s defied the then routine practice to surgically align genitalia to the sex of rearing, as early as possible. However, despite multitude of data showing detrimental effects to genital sensation and sexuality, few patients born with ambiguous genitalia have remained unoperated into adolescence.