Recurrent pyogenic cholangitis: a review of imaging findings and clinical management

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• 作者：Kenneth Eng Ling Kwan ; Vishalkumar G. Shelat ; Cher Heng Tan
• 关键词：Biliary tree ; Cholangitis ; Recurrent pyogenic cholangitis ; Hepatolithiasis
• 刊名：Abdominal Radiology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：42
• 期：1
• 页码：46-56
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Imaging / Radiology; Gastroenterology; Hepatology;
• 出版者：Springer US
• ISSN：2366-0058
• 卷排序：42

文摘

Recurrent pyogenic cholangitis (RPC) is an infective process involving the biliary tree typified by pigmented intraductal calculi with dilatation of the intra- and extrahepatic biliary tree. Previously endemic to South-east Asia, RPC can now be seen in Western countries with the increasing access to international travel and immigration. Affected patients are often plagued by recurrent bouts of cholangitis, and commonly suffer from complications such as abscess formation and biliary strictures. In severe cases, cirrhosis with portal hypertension may develop. The disease is also a known risk factor for cholangiocarcinoma, and can be seen in up to 5% of affected patients. Its exact etiology is unknown, but parasitic infections such as Clonorchis sinensis and Ascaris lumbricoides, ascending bacterial infection with gut flora (Escherichia coli) and low socioeconomic status have been associated strongly with it. This paper reviews the imaging features of the disease, as well as the roles of interventional radiology and surgery with respect to management of the condition.