Development of a Functional Ruthenium(II) Complex that Can Act as a Photoluminescent and Electrochemiluminescent Dual-signaling Probe for Hypochlorous Acid

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• 作者：Xiaojing Yu ; Wenzhu Zhang ; Zhiqiang Ye ; Bo Song ; Jingli Yuan
• 关键词：Ruthenium complex ; Luminescence probe ; Photoluminescence ; Electrochemiluminescence ; Hypochlorous acid
• 刊名：Journal of Fluorescence
• 出版年：2015
• 出版时间：July 2015
• 年：2015
• 卷：25
• 期：4
• 页码：997-1004
• 全文大小：723 KB
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• 作者单位：Xiaojing Yu (1)
  Wenzhu Zhang (1)
  Zhiqiang Ye (1)
  Bo Song (1)
  Jingli Yuan (1)
  
  1. State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian, 116024, People’s Republic of China
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Biomedicine
  Biophysics and Biomedical Physics
  Biotechnology
  Biochemistry
  Analytical Chemistry
  
• 出版者：Springer Netherlands
• ISSN：1573-4994

文摘

A functional ruthenium(II) complex that can act as a probe for response to hypochlorous acid (HOCl) in aqueous media with photoluminescence (PL) and electrochemiluminescence (ECL) dual-signals, [Ru(bpy)2(DB-phen)](PF6)2 [bpy: 2,2-bipyridine; DB-phen: 5-(2,4-dimethoxybenzylamino)-1,10-phenanthroline)], has been designed and synthesized. The complex is highly luminescent both under the light excitation and the electrochemical induction. It can specifically react with HOCl in physiological pH aqueous media to afford its chlorinated derivative, [Ru(bpy)2(DBCA-phen)](PF6)2 [DBCA-phen: 5-(2,4-dimethoxybenzyl-chloroamino)- 1,10-phenanthroline], accompanied by remarkable decreases in its PL and ECL intensities. The PL and ECL abatements of [Ru(bpy)2(DB-phen)](PF6)2 show good linear correlation to the concentration of HOCl with detection limits at low micromolar concentration level, and the PL and ECL responses of the complex to HOCl are highly specific without interferences of other reactive oxygen/nitrogen species. These features enabled [Ru(bpy)2(DB-phen)](PF6)2 to be used as a probe for the highly selective and sensitive detection of HOCl in aqueous media with PL and ECL dual-modes.