Bioconversion of vitamin D3 to calcifediol by using resting cells of Pseudonocardia sp.
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  • 作者:Dae-Jung Kang ; Jong-Hyuk Im ; Jae-Hoon Kang ; Kyoung Heon Kim
  • 关键词:Bioconversion ; Calcifediol ; Central composite design ; Plackett鈥揃urman design ; Pseudonocardia sp. ; Vitamin D3
  • 刊名:Biotechnology Letters
  • 出版年:2015
  • 出版时间:September 2015
  • 年:2015
  • 卷:37
  • 期:9
  • 页码:1895-1904
  • 全文大小:622 KB
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  • 作者单位:Dae-Jung Kang (1) (2)
    Jong-Hyuk Im (2)
    Jae-Hoon Kang (2)
    Kyoung Heon Kim (1)

    1. Department of Biotechnology, Graduate School, Korea University, Seoul, 136-713, Republic of Korea
    2. Research Laboratories, Ildong Pharmaceutical, Hwaseong, 445-170, Republic of Korea
  • 刊物类别:Biomedical and Life Sciences
  • 刊物主题:Life Sciences
    Microbiology
    Biotechnology
    Applied Microbiology
    Biochemistry
  • 出版者:Springer Netherlands
  • ISSN:1573-6776
文摘
Objectives Resting cells of Pseudonocardia sp. KCTC 1029BP were used for the bioconversion of vitamin D3 to calcifediol which is widely used to treat osteomalacia and is industrially produced by chemical synthesis.

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