Gut microbiota lipopolysaccharide accelerates inflamm-aging in mice
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- 作者：Kyung-Ah Kim ; Jin-Ju Jeong ; Sul-Young Yoo ; Dong-Hyun Kim
- 关键词：Inflamm ; aging ; Gut microbiota ; Lipopolysaccharide ; p16 ; SAMHD1
- 刊名：BMC Microbiology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：16
- 期：1
- 全文大小：1,363 KB
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Jin-Ju Jeong (1)
Sul-Young Yoo (1)
Dong-Hyun Kim (1)
1. Department of Life and Nanopharmaceutical Sciences, College of Pharmacy, Kyung Hee University, 1, Hoegi, Dongdaemun-ku, Seoul, 130-701, Korea
2. Department of Food and Nutrition, Song Won University, 73, Songamro, Nam-gu, Gwangju, 503-742, Korea - 刊物主题：Microbiology; Biological Microscopy; Fungus Genetics; Parasitology; Virology; Life Sciences, general;
- 出版者：BioMed Central
- ISSN：1471-2180
文摘
Background The constitutive inflammation that characterizes advanced age is termed inflamm-aging. This process is associated with age-related changes to immune homeostasis and gut microbiota. We investigated the relationship between aging and gut microbiota lipopolysaccharide (LPS)-inducible inflammation.