miR-27b inhibits fibroblast activation via targeting TGFβ signaling pathway
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- 作者：Xiangming Zeng ; Chaoqun Huang ; Lakmini Senavirathna ; Pengcheng Wang…
- 关键词：miR ; 27b ; Fibroblast activation ; TGFβ ; Idiopathic pulmonary fibrosis
- 刊名：BMC Cell Biology
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：18
- 期：1
- 全文大小：833KB
- 刊物主题：Cell Biology; Biological Microscopy; Life Sciences, general;
- 出版者：BioMed Central
- ISSN：1471-2121
- 卷排序：18
文摘
BackgroundMicroRNAs are a group of small RNAs that regulate gene expression at the posttranscriptional level. They regulate almost every aspect of cellular processes. In this study, we investigated whether miR-27b regulates pulmonary fibroblast activation.