Anaplastisch großzelliges Lymphom CD30(+) ALK(+)

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• 作者：L. Kollarikova ; M. Heizerova ; M. Simaljakova
• 关键词：Primary systemic lymphoma ; Histology ; Immunophenotyping ; Chemotherapy ; Radiotherapy
• 刊名：Der Hautarzt
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：67
• 期：4
• 页码：304-307
• 全文大小：467 KB
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• 作者单位：L. Kollarikova (1)
  M. Heizerova (1)
  M. Simaljakova (1)
  
  1. Klinik für Dermatologie und Venerologie der Medizinischen Fakultät, Comenius Universität, Mickiewiczova 13, 813 69, Bratislava, Slowakei
  
• 刊物主题：Dermatology; Immunology; Allergology; Proctology;
• 出版者：Springer Berlin Heidelberg
• ISSN：1432-1173

文摘

We present a case of primary systemic anaplastic large-cell lymphoma, which manifested itself through skin involvement in a 32-year-old man. Only the third histological investigation with immunophenotyping resulted in the correct diagnosis of CD30(+) ALK(+) anaplastic large cell lymphoma. After combined chemotherapy and adjuvant radiotherapy, complete remission of the disease was achieved and one year after completion of therapy no relapse occurred. The diagnostic pitfalls and therapeutic options are discussed.