Preemptive scalp infiltration with 0.5?% ropivacaine and 1?% lidocaine reduces postoperative pain after craniotomy
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  • 作者:Jie Song ; Li Li ; Pengtao Yu ; Tao Gao ; Kui Liu
  • 关键词:Preemptive analgesia ; Scalp infiltration ; Ropivacaine ; Craniotomy
  • 刊名:Acta Neurochirurgica
  • 出版年:2015
  • 出版时间:June 2015
  • 年:2015
  • 卷:157
  • 期:6
  • 页码:993-998
  • 全文大小:408 KB
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  • 作者单位:Jie Song (1)
    Li Li (2)
    Pengtao Yu (1)
    Tao Gao (2)
    Kui Liu (1)

    1. Departments of Neurological Surgery, Union Medical Center, Tianjin, China
    2. Departments of Anesthesiology, Union Medical Center, 190#, Jieyuan Road, Hongqiao District, Tianjin, China, 300121
  • 刊物主题:Neurosurgery; Interventional Radiology; Neuroradiology; Neurology; Surgical Orthopedics; Minimally Invasive Surgery;
  • 出版者:Springer Vienna
  • ISSN:0942-0940
文摘
Background In order to reduce the consequences of narcotic-related side effects and provide effective analgesia after craniotomy, we conducted a randomized trial to compare the analgesic efficacy of preemptive scalp infiltrations with 1?% lidocaine and 0.5?% ropivacaine on the postoperative pain. Methods Sixty adult patients scheduled for craniotomy were enrolled. A solution contained 0.5?% ropivacaine and 1?% lidocaine (40?ml) was prepared. In group A, local anesthetic was injected throughout the entire thickness of the scalp before skin incision. In group B, it was injected before skin closure. Additional intravenous injection and patient-controlled analgesia with morphine was used to control postoperative pain if the verbal numerical rating scale-gt;-. Cumulative morphine consumption; numerical rating scale of pain at 1, 2, 4, 6, 8, 12, and 24?h; postoperative nausea, vomiting, and respiratory depression, were recorded for 24?h after the operation. Results Postoperative pain scores were lower in group A than in group B within the first 6?h after surgery. Mean time to demand for postoperative analgesic was statistically (p-lt;-.001) delayed in group A 300 (240, 360) min compared to group B 150 (105, 200) min. Ten patients in group A received morphine analgesia was half less than 21 patients in group B (p-lt;-.006). The median morphine consumption in 24?h after operation in group A 10.5 (8, 15) mg was less than that in group B 28 (22.5, 30.5) mg (p-lt;-.001). Conclusions Preemptive scalp infiltration with 0.5?% ropivacaine and 1?% lidocaine provides effective postoperative analgesia after craniotomy.

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