Genetic and molecular characterization of a novel reassortant H2N8 subtype avian influenza virus isolated from a domestic duck in Zhejiang Province in China

详细信息    查看全文

• 作者：Haibo Wu ; Xiuming Peng ; Xiaorong Peng ; Linfang Cheng ; Nanping Wu
• 关键词：Avian influenza virus ; H2N8 ; Genetic analysis ; Virus reassortment ; Domestic ducks
• 刊名：Virus Genes
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：52
• 期：6
• 页码：863-866
• 全文大小：756 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Medical Microbiology
  Virology
  Plant Sciences
  
• 出版者：Springer Netherlands
• ISSN：1572-994X
• 卷排序：52

文摘

The circulation of the H2 subtype influenza viruses in domestic animals increases the risk of human exposure to these viruses. An H2N8 avian influenza virus (AIV) was isolated from a domestic duck during AIV surveillance of poultry in live poultry markets (LPMs) in Zhejiang Province, Eastern China, in 2013. The phylogenetic trees suggested that this strain is a novel reassortant virus derived from multiple AIV subtypes from aquatic birds and poultry in Eastern Asia. Although this reassortant strain exhibited low pathogenicity in mice, it was able to replicate in the lungs of the mice without prior adaptation. Continued surveillance of domestic ducks in LPMs is required for early detection of AIV outbreaks in poultry and humans.