Spontaneous pneumothorax associated with talc pulmonary granulomatosis after cocaine inhalation

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• 作者：Alfonso Fiorelli ; Marina Accardo…
• 关键词：Cocaine ; Pneumothorax ; Lung ; Granulomatosis ; Talc
• 刊名：General Thoracic and Cardiovascular Surgery
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：64
• 期：3
• 页码：174-176
• 全文大小：885 KB
• 参考文献：1.Ward S, Heyneman LE, Reittner P, Kazerooni EA, Godwin JD, Muller NL. Talcosis associated with IV abuse of oral medications: CT findings. Am J Roentgenol. 2000;174:789–93.CrossRef
  2.Pare JP, Cote G, Fraser RS. Longterm follow-up of drug abusers with intravenous talcosis. Am Rev Respir Dis. 1989;139:233–41.CrossRef PubMed
  3.Roberts WC. Pulmonary talc granulomas, pulmonary fibrosis, and pulmonary hypertension resulting from intravenous injection of talc-containing drugs intended for oral use. Proc (Bayl Univ Med Cent). 2002;15:260–1.PubMed PubMedCentral
  4.Oubeid M, Bickel JT, Ingram EA, Scott GC. Pulmonary talc granulomatosis in a cocaine sniffer. Chest. 1990;98:237–9.CrossRef PubMed
  5.Rhodes RE, Chiles C, Vick WW. Talc granulomatosis presenting as spontaneous pneumothorax. South Med J. 1991;84:929–30.CrossRef PubMed
  6.Caceres M, Braud R, Garrett HE Jr. An unusual presentation of spontaneous pneumothorax secondary to talc-induced pulmonary granulomatosis. Ann Thorac Surg. 2009;87:1941–3.CrossRef PubMed
  7.Cooper CB, Bai TR, Heyderman E, Corrin B. Cellulose granuloma in the lungs of a cocaine sniffer. Br Med J (Clin Res Ed). 1983;286:2021–2.CrossRef
  8.Abraham JL, Brambilla C. Particle size for differentiation between inhalation and injection pulmonary talcosis. Environ Res. 1980;21:94–6.CrossRef PubMed
  9.Fiorelli A, Accardo M, Vicidomini G, Messina G, Laperuta P, Santini M. Does cannabis smoking predispose to lung bulla formation? Asian Cardiovasc Thorac Ann. 2014;22:65–71.CrossRef PubMed
  10.Fiorello A, Vicidomini G, Santini M. Marijuana smokers and lung bullae. Eur J Cardiothorac Surg. 2008;34:706–7.CrossRef PubMed
  
• 作者单位：Alfonso Fiorelli (1)
  Marina Accardo (2)
  Francesco Rossi (3)
  Mario Santini (1)
  
  1. Thoracic Surgery Unit, Second University of Naples, Piazza Miraglia, due, 80138, Naples, Italy
  2. Department of Morphopathology, Second University of Naples, Naples, Italy
  3. Laboratory of Applied Biotechnology, Department of Anesthesiology, Surgery, and Emergency Sciences, Second University of Naples, Naples, Italy
  
• 刊物主题：Thoracic Surgery; Cardiac Surgery; Cardiology; Surgical Oncology;
• 出版者：Springer Japan
• ISSN：1863-6713

文摘

We report a case of recurrent spontaneous pneumothorax in a patient with cocaine abuse through inhalation alone. He underwent thoracoscopic apical lung resection with mechanical pleurodesis. Despite the lack of significant radiological features of talc induced pulmonary granulomatosis, pathological findings showed granulomas with foreign materials suggestive of being talc. Electronic microscopy showed that the size of talc particles were <4.0 µm and thus small enough to reach the alveoli.