Inhaled nitric oxide as adjunctive therapy for severe malaria: a randomized controlled trial
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- 作者：Michael T. Hawkes ; Andrea L. Conroy ; Robert O. Opoka ; Laura Hermann…
- 关键词：Nitric oxide ; Endothelium ; Severe malaria ; Child ; Randomized controlled trial
- 刊名：Malaria Journal
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：14
- 期：1
- 全文大小：1,469 KB
- 刊物主题：Parasitology; Infectious Diseases; Tropical Medicine;
- 出版者：BioMed Central
- ISSN：1475-2875
文摘
Background Severe malaria remains a major cause of childhood mortality globally. Decreased endothelial nitric oxide is associated with severe and fatal malaria. The hypothesis was that adjunctive inhaled nitric oxide (iNO) would improve outcomes in African children with severe malaria.