A phase II study of the HSP90 inhibitor AUY922 in chemotherapy refractory advanced pancreatic cancer

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• 作者：D. J. Renouf ; D. Hedley ; M. K. Krzyzanowska…
• 关键词：Pancreatic cancer ; AUY922 ; Phase II
• 刊名：Cancer Chemotherapy and Pharmacology
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：78
• 期：3
• 页码：541-545
• 全文大小：419 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Cancer Research
  Pharmacology and Toxicology
  Oncology
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-0843
• 卷排序：78

文摘

ObjectivesAUY922 is a novel heat shock protein inhibitor with preclinical activity in pancreatic cancer. This phase II study evaluated the efficacy of AUY922 in patients with advanced pancreatic cancer previously treated with chemotherapy.