Botulinum Toxin Injection for Treatment of Chronic Anal Fissure: Is There Any Dose-Dependent Efficiency? A Meta-Analysis

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• 作者：Adam Bobkiewicz ; Wojciech Francuzik ; Lukasz Krokowicz…
• 刊名：World Journal of Surgery
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：40
• 期：12
• 页码：3064-3072
• 全文大小：1,104 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Surgery
  Abdominal Surgery
  Cardiac Surgery
  General Surgery
  Thoracic Surgery
  Vascular Surgery
  
• 出版者：Springer New York
• ISSN：1432-2323
• 卷排序：40

文摘

BackgroundChronic anal fissure (CAF) is a linear split of the anoderm. The minimally invasive management of CAF such as botulinum toxin (BT) injection is recommended. However, the exact efficient dose of BT, number of injections per session and the injection sites are still debatable. The aim of this analysis was to assess the dose-dependent efficiency of botulinum toxin injection for CAF.