Human bone marrow-derived and umbilical cord-derived mesenchymal stem cells for alleviating neuropathic pain in a spinal cord injury model
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- 作者：Mahmoud Yousefifard ; Farinaz Nasirinezhad…
- 关键词：Spinal cord injuries ; Neuropathic pain ; Stem cells ; Electrophysiologic techniques ; Wind up
- 刊名：Stem Cell Research & Therapy
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：7
- 期：1
- 全文大小：1,690 KB
- 刊物主题：Stem Cells; Cell Biology;
- 出版者：BioMed Central
- ISSN：1757-6512
文摘
Background Stem cell therapy can be used for alleviating the neuropathic pain induced by spinal cord injuries (SCIs). However, survival and differentiation of stem cells following their transplantation vary depending on the host and intrinsic factors of the cell. Therefore, the present study aimed to determine the effect of stem cells derived from bone marrow (BM-MSC) and umbilical cord (UC-MSC) on neuropathic pain relief.