The impact of new screen-detected and previously known type 2 diabetes on health-related quality of life: a population-based study in Qingdao, China

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• 作者：Yanlei Zhang ; Jianping Sun ; Zengchang Pang ; Xiaoyong Wang…
• 关键词：Health ; related quality of life ; 15D instrument ; Diabetes
• 刊名：Quality of Life Research
• 出版年：2014
• 出版时间：October 2014
• 年：2014
• 卷：23
• 期：8
• 页码：2319-2326
• 全文大小：329 KB
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• 作者单位：Yanlei Zhang (1)
  Jianping Sun (2)
  Zengchang Pang (2)
  Xiaoyong Wang (3)
  Weiguo Gao (4)
  Feng Ning (2)
  Jie Ren (5)
  Anil Kapur (6)
  Harri Sintonen (1)
  Qing Qiao (1) (7)
  
  1. Department of Public Health, Hjelt Institute, University of Helsinki, Mannerheimintie 172, PL41, 00014, Helsinki, Finland
  2. Qingdao Municipal Centre for Disease Control and Prevention, Qingdao, Shandong, China
  3. Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China
  4. AstraZeneca, Shanghai, China
  5. Department of Non-communicable Disease Prevention, Shandong Province Centre for Disease Control and Prevention, Jinan, Shandong, China
  6. World Diabetes Foundation, Gentofte, Denmark
  7. R&D, AstraZeneca, M?lndal, Sweden
  
• ISSN：1573-2649

文摘

Aims To examine and compare health-related quality of life (HRQoL) in people with previously known diabetes, new screen-detected asymptomatic diabetes and people without diabetes. Methods HRQoL of 4,613 individuals who participated in a population-based cross-sectional diabetes survey in Qingdao, China, in 2009, was assessed using the 15D instrument. A Tobit regression model to estimate the effects of diabetes on HRQoL separate from effects of other health determinants was constructed. Results Among the surveyed population, 220 (4.8?%) individuals had previously known diabetes and 531 (11.5?%) individuals had new screen-detected diabetes, defined by fasting plasma glucose ?.0?mmol/l and/or 2-h plasma glucose ?1.1?mmol/l. The age-, gender-, and BMI-adjusted mean 15D score of people without diabetes, with new screen-detected diabetes, and previously known diabetes was 0.975, 0.975, and 0.964, respectively, for urban and 0.971, 0.972, and 0.960, respectively, for rural participants. HRQoL overall and on all the dimensions (p?p? Conclusion Health-related quality of life was impaired in people with previously known diabetes who had co-morbid conditions, but was largely unaltered in people with newly detected asymptomatic diabetes as compared to people without diabetes.