Novel SNPs in IL-17F and IL-17A genes associated with somatic cell count in Chinese Holstein and Inner-Mongolia Sanhe cattle

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• 作者：Tahir Usman ; Yachun Wang ; Chao Liu…
• 关键词：Chinese Holstein ; Inner Mongolia Sanhe cattle ; Interleukin 17A ; Interleukin 17F ; Mastitis susceptibility
• 刊名：Journal of Animal Science and Biotechnology
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：8
• 期：1
• 全文大小：875KB
• 刊物主题：Agriculture; Biotechnology; Food Science; Animal Genetics and Genomics; Animal Physiology;
• 出版者：BioMed Central
• ISSN：2049-1891
• 卷排序：8

文摘

BackgroundBovine mastitis is the most common and costly disease of lactating cattle worldwide. Apart from milk somatic cell count (SCC) and somatic cell score (SCS), serum cytokines such as interleukin-17 (IL-17) and interleukin-4 (IL-4) may also be potential indicators for bovine mastitis. The present study was designed to investigate the effects of single nucleotide polymorphisms (SNPs) in bovine IL-17F and IL-17A genes on SCC, SCS and serum cytokines in Chinese Holstein and Inner-Mongolia Sanhe cattle, and to compare the mRNA expression variations of the cows with different genotypes.