Chiral Diaminocarbene Complexes, Synthesis and Application in Asymmetric Catalysis

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• 作者：Sylvain Roland ; Pierre Mangeney
• 关键词：Azolium salts ; N ; heterocyclic carbenes ; transition metal complexes ; asymmetric catalysis
• 刊名：Topics in Organometallic Chemistry
• 出版年：2005
• 出版时间：2005
• 年：2005
• 卷：15
• 期：1
• 页码：p.191
• 全文大小：1,669 KB
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Organometallic Chemistry
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1616-8534

文摘

The synthetic routes to optically pure N-heterocyclic carbene (NHC) complexes and their application in asymmetric catalysis is reviewed. Chiral N-heterocyclic carbenes which are mainly generated from the corresponding azolium salts can be used as ligands to prepare various complexes with transition metals. However, only a few of them have been used in asymmetric catalysis and reported examples where chiral NHC complexes give good enantioselectivity are still rare even if excellent levels of enantioselectivity have been reached (up to >99% ee). This chapter describes the general properties of this family of ligand, the synthesis of the chiral azolium salts, the preparation of NHC-metal complexes and the asymmetric transformations catalyzed by palladium, rhodium, ruthenium, iridium and copper complexes.