Can inhibiting insulin/IGF signaling with dietary carbohydrate restriction play a role in treatment/prevention of cancers?

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• 作者：Eugene J Fine (47)
  C Segal-Isaacson (47)
  Silvia Herzkopf (48)
  Joseph Sparano (49)
  Maria Romano (48)
  Richard Feinman (50)
  Nora Tomuta (48)
  Amanda Bontempo (48)
  Abdissa Negassa (51)
  
• 刊名：Cancer & Metabolism
• 出版年：2014
• 出版时间：May 2014
• 年：2014
• 卷：2
• 期：1-supp
• 全文大小：
• 参考文献：1. Lann D, LeRoith D: The role of endocrine insulin-like growth factor-I and insulin in breast cancer. / J Mammary Gland Biol Neoplasia 2008, 13:371鈥?79. CrossRef
  2. Fine EJ, Miller A, Quadros EV, Sequeira JM, Feinman RD: Acetoacetate reduces growth and ATP concentration in cancer cell lines which over-express uncoupling protein 2. / Cancer Cell International 2009, 9:14. CrossRef
  3. Zhou W, Simpson PJ, McFadden JM, / et al.: Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells. / Cancer Res 2003, 63:7330鈥?337.
  4. Bortner CD, Sifre MI, Cidlowski JA: Cationic gradient reversal and cytoskeleton-independent volume regulatory pathways define an early stage of apoptosis. / J Biol Chem 2008, 283:7219鈥?229. CrossRef
  5. Yao JC, Lombard-Bohas C, Baudin E, Kvols LK, Rougier P, Ruszniewski P, / et al.: Daily oral everolimus activity in patients with metastatic pancreatic neuroendocrine tumors after failure of cytotoxic chemotherapy: a phase II trial. / J Clin Oncol 2010, 28:69鈥?6. CrossRef
  6. Luo Z, Zang M, Guo W: AMPK as a metabolic tumor suppressor: control of metabolism and cell growth. / Future Oncol 2010, 6:457鈥?70. CrossRef
  
• 作者单位：Eugene J Fine (47)
  C Segal-Isaacson (47)
  Silvia Herzkopf (48)
  Joseph Sparano (49)
  Maria Romano (48)
  Richard Feinman (50)
  Nora Tomuta (48)
  Amanda Bontempo (48)
  Abdissa Negassa (51)
  
  47. Nuclear Medicine, Albert Einstein College of Medicine, Bronx, NY, USA
  48. Radiation Oncology, Montefiore Medical Center, Bronx, NY, USA
  49. Medicine, Montefiore Medical Center, Bronx, NY, USA
  50. Cell Biology, SUNY-Downstate Medical Center, Brooklyn, NY, USA
  51. Epidemiology and Public Health, Albert Einstein College of Medicine, Bronx, NY, USA
  
• ISSN：2049-3002

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