Genetic diversity of Plasmodium falciparum parasite by microsatellite markers after scale-up of insecticide-treated bed nets in western Kenya
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- 作者：Wangeci Gatei ; John E. Gimnig ; William Hawley ; Feiko ter Kuile…
- 关键词：Plasmodium falciparum ; Population structure ; Genetic diversity ; ITNs ; Transmission
- 刊名：Malaria Journal
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：14
- 期：1
- 全文大小：1,190 KB
- 刊物主题：Parasitology; Infectious Diseases; Tropical Medicine;
- 出版者：BioMed Central
- ISSN：1475-2875
文摘
Background An initial study of genetic diversity of Plasmodium falciparum in Asembo, western Kenya showed that the parasite maintained overall genetic stability 5 years after insecticide-treated bed net (ITN) introduction in 1997. This study investigates further the genetic diversity of P. falciparum 10 years after initial ITN introduction in the same study area and compares this with two other neighbouring areas, where ITNs were introduced in 1998 (Gem) and 2004 (Karemo).