Serum hepcidin-25 and response to intravenous iron in patients with non-dialysis chronic kidney disease

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• 作者：Sourabh Chand ; Douglas G. Ward ; Zhi-Yan Valerie Ng ; James Hodson…
• 关键词：Hepcidin ; Iron ; CKD ; Haemoglobin ; Prediction ; Utility
• 刊名：Journal of Nephrology
• 出版年：2015
• 出版时间：February 2015
• 年：2015
• 卷：28
• 期：1
• 页码：81-88
• 全文大小：
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• 作者单位：Sourabh Chand (1) (2)
  Douglas G. Ward (3)
  Zhi-Yan Valerie Ng (2)
  James Hodson (4)
  Heidi Kirby (2)
  Patricia Steele (2)
  Irina Rooplal (2)
  Ferly Bantugon (2)
  Tariq Iqbal (5)
  Chris Tselepis (3)
  Mark T. Drayson (6)
  Alison Whitelegg (6)
  Marie Chowrimootoo (2)
  Richard Borrows (1) (2)
  
  1. Renal Department, First Floor, Centre for Translational Inflammation Research, Queen Elizabeth Hospital Birmingham, University of Birmingham, Birmingham, B15 2WB, UK
  2. Department of Nephrology and Kidney Transplantation, Queen Elizabeth Hospital Birmingham, Birmingham, B15 2WB, UK
  3. School of Cancer Sciences, University of Birmingham, Birmingham, B15 2TT, UK
  4. Department of Statistics, Wolfson Laboratory, Old Queen Elizabeth Hospital, Birmingham, B15 2TH, UK
  5. Department of Gastroenterology, Queen Elizabeth Hospital Birmingham, Birmingham, B15 2WB, UK
  6. Department of Immunology, University of Birmingham, Birmingham, B15 2WB, UK
  
• 刊物类别：Nephrology; Urology;
• 刊物主题：Nephrology; Urology;
• 出版者：Springer International Publishing
• ISSN：1724-6059

文摘

Background Hepcidin-25 is an iron regulator which reduces iron absorption and promotes sequestration in the reticulo-endothelial system. We investigated hepcidin and traditional iron storage marker utility in predicting haemoglobin increment following bolus intravenous iron.