Prevalence of dementia and major dementia subtypes in Spanish populations: A reanalysis of dementia prevalence surveys, 1990-2008
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- 作者：Jesús de Pedro-Cuesta (1)
Javier Virués-Ortega (1)
Saturio Vega (2)
Manuel Seijo-Martínez (3)
Pedro Saz (4)
Fernanda Rodríguez (5)
Angel Rodríguez-Laso (6)
Ramón Re?é (7)
Susana Pérez de las Heras (8)
Raimundo Mateos (9)
Pablo Martínez-Martín (1)
Ignacio Mahillo-Fernandez (1)
Secundino López-Pousa (11)
Antonio Lobo (5)
Llinàs Jordi Reglà (11)
Jordi Gascón (7)
Francisco José García (12)
Manuel Fernández-Martínez (13)
Raquel Boix (1)
Félix Bermejo-Pareja (14)
Alberto Bergareche (15)
Julián Benito-León (15) (16)
Ana de Arce (17)
José Luis del Barrio (1) - 刊名：BMC Neurology
- 出版年：2009
- 出版时间：December 2009
- 年：2009
- 卷：9
- 期：1
- 全文大小：1000KB
- 参考文献：1. Del Barrio JL, de Pedro-Cuesta J, Boix R, Acosta J, Bergareche A, Bermejo-Pareja F, Gabriel R, / et al.: Dementia, Stroke and Parkinson's Disease in Spanish Populations: A Review of Door-to-Door Prevalence Surveys. / Neuroepidemiology 2005, 24:179-88. CrossRef
2. European Commission: Health statistics: Atlas on mortality in the European Union. Luxemburg: Office for official publications of the European communities 2009, 128-29.
3. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, / et al.: Meta-analysis of observational studies in epidemiology. / JAMA 2000, 283:2008-012. ma.283.15.2008">CrossRef
4. Bermejo-Pareja F, Vega S, Morales J, Díaz J, López L, Parra D, / et al.: Prevalence of stroke in two samples (rural and urban) of old people in Spain. A pilot door-to-door study carried out by health professionals. / Neurología 1997, 12:157-61.
5. Lobo A, Saz P, Marcos G, Día JL, de la Cámara C: The prevalence of dementia and depression in the elderly community in a southern European population. The Zaragoza Study. / Arch Gen Psychiatry 1995, 52:497-06.
6. Lobo A, Launer LJ, Fratiglioni L, Andersen K, Di Carlo A, Breteler MMB, / et al.: Prevalence of dementia and major subtypes in Europe: a collaborative study of population-based cohorts. / Neurology 2000,54(Suppl 5):S4-S9.
7. Manubens JM, Martínez-Lage JM, Lacruz F, Muruzabal J, Larumbe R, Guarch C, Urrutia T, Sarrasqueta P, Martínez-Lage P, Rocca WA: Prevalence of Alzheimer's disease and Other Dementing Disorders in Pamplona, Spain. / Neuroepidemiol 1995, 14:155-4. CrossRef
8. Morales JM, Bermejo FP, Benito-Leon J, Rivera-Navarro J, Trincado R, Gabriel SR, Vega S, NEDICES Study Group: Methods and demographic findings of the baseline survey of the NEDICES cohort: a door-to-door survey of neurological disorders in three communities from Central Spain. / Public Health 2004, 118:426-33. CrossRef
9. García FJ, Sánchez MA, Pérez A, Martín E, Marsal C, Rodríguez G, / et al.: Prevalencia de demencia y de sus subtipos principales en sujetos mayores de 65 a?os: efecto de la educación y ocupación. Estudio Toledo. / Med Clin 2001, 116:401-07.
10. Zunzunegui MV, del Ser T, Rodríguez-Laso A, García de Yébenes MJ, Domingo J, / et al.: Demencia no detectada y utilización de los servicios sanitarios implicaciones para la atención primaria. / Aten Primaria 2003, 31:581-86. CrossRef
11. Vilalta-Franch J, López-Pousa S, Llinás-Reglá J: Prevalencia de demencias en una zona rural. Estudio de Girona. / Rev Neurol 2000, 30:1026-032.
12. Coria F, Gómez-de-Caso JA, Mínguez L, Rodríguez-Artalejo F, Claveía LE: Prevalence of age-associated memory impairment and dementia in a rural community. / J Neurol Neurosurg Psychiatry 1993, 56:973-76. CrossRef
13. Pi J, Olivé JM, Roca J, Masana L: Prevalence of Dementia in a Semi-Rural Population of Catalunya, Spain. / Neuroepidemiol 1996, 15:33-1. CrossRef
14. Matías-Guiu J, Vi?ets C, Falip R, López-Arlandis J, Oltra A, Canet T: Epidemiología descriptiva del accidente isquémico transitorio: estudio en Muro d'Alcoi. / Rev Neurol 1995, 23:422-24.
15. Bergareche A, De-la-Puente E, López-de-Munain A, Sarasqueta C, De-Arce A, Poza JJ, Martí-Massó JF: Prevalence of Parkinson's disease and other types of Parkinsonism. A door-to-door survey in Bidasoa, Spain. / J Neurol 2004, 251:340-45. CrossRef
16. Bergareche A, De la Puente E, López de Munain A, Sarasqueta C, De Arce A, Poza JJ, Martí-Massó JF: Prevalence of essential tremor: a door-to-door survey in Bidasoa, Spain. / Neuroepidemiology 2001, 20:125-28. CrossRef
17. Gascón-Bayarri J, Re?é R, Del Barrio JL, De Pedro-Cuesta J, Ramón JM, Manubens JM, / et al.: Prevalence of dementia subtypes in El Prat de Llobregat, Catalonia, Spain: The PRATICON Study. / Neuroepidemiology 2007, 28:224-34. CrossRef
18. Fernández M, Castro J, Pérez S, Mandaluniz A, Gordejuela M, Zarranz JJ: Prevalencia de demencia en Mungialde (Vizcaya). / Neurología 2006, 21:551-77.
19. Fernández M, Castro J, Pérez S, Mandaluniz A, Gordejuela M, Zarranz JJ: Risk factors for dementia in the epidemiological study of Munguialde County (Basque Country-Spain). / BMC Neurology 2008, 8:39. CrossRef
20. Gavrilla D, Antúnez C, Tormo MJ, Navarro G, Parrilla JM, García R, / et al.: Prevalencia de demencia y deterioro cognitivo leve en la región de Murcia. Estudio ARIADNA [Abstract]. / Gac Sanit 2005.,19(Supl 1):
21. Lobo A, Saz P, Marcos G, Dia JL, De-la-Camara C, Ventura T, Monta?es JA, Lobo-Escolar A, Aznar S, ZARADEMP Workgroup: Prevalence of dementia in a southern European population in two different time periods: The ZARADEMP Project. / Acta Psychiatr Scand 2007, 116:299-07. CrossRef
22. Barrado MJ, de Pedro-Cuesta J, Almazán J: Stroke mortality in Spain 1901-984. / Neuroepidemiology 1993, 12:148-57. CrossRef
23. Medrano MJ, Sierra MJ, Almazan J, Olalla MT, López-Abente G: The association of dietary folate, B 12 and B 6 with cardiovascular mortality in Spain. An ecological analysis. / Am J Public Health 2000, 90:1636-638. CrossRef
24. Del Barrio J, Medrano M, Arce A, Bergareche A, Bermejo F, Diaz J, / et al.: Prevalence of vascular risk factors among Spanish populations aged 70 years and over, as reported in door-to-door studies on neurological diseases. / Neurologia 2007, 22:138-46.
25. Lopez-Abente G, Pollán , Escolar A, Errezola M, Abraira V: Atlas de mortalidad por cancer y otras causas en Espa?a, 1978-992. / Madrid: Instituto de Salud Carlos III 2001, 154-55.
26. Wolff LE, Woods JP, Reid J: Do general practitioners and old age psychiatrists differ in their attitudes to dementia? / Int J Geriatr Psychiatry 1995, 10:63-9. CrossRef
27. López-Pousa S, Vilalta-Franch J, Llinas-Regla J, Garré-Olmo J, Roman GC: Incidence of dementia in a rural community in Spain: the Girona cohort study. / Neuroepidemiol 2004, 23:170-77. CrossRef
28. Roman GC: Defining dementia: Clinical criteria for the diagnosis of vascular dementia. / Acta Neurol Scand 2002,178(Suppl 1):6-. CrossRef
29. Verhery FR, Lodder J, Rozendall N, Jolles J: Comparison of seven sets of criteria used for the diagnosis of vascular dementia. / Neuroepidemiol 1996, 15:166-72. CrossRef
30. Weterling T, Kanitz RD, Borgis KJ: Comparision of different diagnostic criteria used for vascular dementia (ADDT, DSM-IV, ICD-10, NINDS-AIREN). / Stroke 1996, 27:30-6.
31. Roelands M, Wostyn P, Dom H, Baro F: The prevalence of dementia in Belgium: A population-based door-to-door survey in a rural community. / Neuroepidemiol 1994, 13:155-61. CrossRef
32. Fratiglioni L, Grut M, Forsell Y, Viitanen M, Grafstr?m M, Holmén K, Ericsson K, B?ckman L, Ahlbom A, Winblad B: Prevalence of Alzheimer's disease and other dementias in an elderly urban population: Relationship with age, sex and education. / Neurology 1991, 41:1886-892.
33. Breteler MMB, Ouweland FA, Grobbee DE, Hofman A: A Community-Based Study of Dementia: the Rotterdam Elderly Study. / Neuroepidemiology 1992,11(Suppl 1):23-8. CrossRef
34. Maggi S, Zucchetto M, Grigoletto F, Baldereschi M, Candelise L, Scarpini E, Scarlato G, Amaducci L: The Italian Longitudinal Study on Aging (ILSA): design and methods. / Aging Clin Exp Res 1994, 6:464-73.
35. Saunders PA, Copeland JRM, Dewey ME, Gilmore C, Larkin BA, Phaterpekar H, Scott A: The prevalence of Dementia, Depression and Neurosis in Later Life: the Liverpool MRC-ALPHA Study. / Int J Epidemiol 1993, 22:838-47. CrossRef
36. Tognoni G, Ceravolo R, Nucciarone B, Bianchi F, Dell'Agnello G, Ghicopulos I, Siciliano G, Murri L: From mild cognitive impairment to dementia: a prevalence study in a district of Tuscany, Italy. / Acta Neurol Scand 2005, 112:65-1. CrossRef
37. Rahkonen T, Eloniemi-Sulkava U, Rissanen S, Vatanen A, Viramo P, Sulkava R: Dementia with Lewy bodies according to the consensus criteria in a general population aged 75 years or older. / J Neurol Neurosurg Psychiatry 2003, 74:720-24. CrossRef
38. Stevens T, Livingston G, Kitchen G, Manela M, Walker Z, Katona C: Islington study of dementia subtypes in the community. / Br J Psychiatry 2002, 180:270-76. CrossRef
39. Rothman KJ, Greenland S: Measures of disease frequency. / Modern Epidemiology / 2 Edition / (Edited by: Rothman KJ, Greenland S). Philadelphia: Lippincott-Raven Publishers 1998, 42-5.
40. Rascovsky K, Salmon DP, Lipton AM, Leverenz JB, DeCArli C, Jagust WJ, / et al.: Rate of progression differs in frontotemporal dementia and Alzheimer disease. / Neurology 2005, 65:397-03. CrossRef
41. Sheng B, Cheng LF, Law CB, Li HL, Yeung KM, Lau KK: Coexisting cerebral infarction in Alzheimer's disease is associated with fast dementia rogression. / J Am Geriatr Soc 2007, 55:918-22. CrossRef
42. Bermejo F, Gabriel R, Vega S, Morales JM, Rocca W, Anderson D: Problems and issues with door-to-door, two-phase surveys: an illustration from central Spain. / Neuroepidemiol 2001, 20:225-31. CrossRef
43. The pre-publication history for this paper can be accessed here: medcentral.com/1471-2377/9/55/prepub" class="a-plus-plus">http://www.biomedcentral.com/1471-2377/9/55/prepub - 作者单位：Jesús de Pedro-Cuesta (1)
Javier Virués-Ortega (1)
Saturio Vega (2)
Manuel Seijo-Martínez (3)
Pedro Saz (4)
Fernanda Rodríguez (5)
Angel Rodríguez-Laso (6)
Ramón Re?é (7)
Susana Pérez de las Heras (8)
Raimundo Mateos (9)
Pablo Martínez-Martín (1)
Ignacio Mahillo-Fernandez (1)
Secundino López-Pousa (11)
Antonio Lobo (5)
Llinàs Jordi Reglà (11)
Jordi Gascón (7)
Francisco José García (12)
Manuel Fernández-Martínez (13)
Raquel Boix (1)
Félix Bermejo-Pareja (14)
Alberto Bergareche (15)
Julián Benito-León (15) (16)
Ana de Arce (17)
José Luis del Barrio (1)
1. National Centre for Epidemiology, CIBERNED and Alzheimer' Disease Research Unit, Carlos III Institute of Public Health, Madrid, Spain
2. Primary Care Administration, Segovia, Spain
3. Neurology Unit, Salnés Hospital, Pontevedra, Spain
4. Department of Medicine and Psychiatry, Zaragoza University, Zaragoza, Spain
5. Neurology Unit, Segovia Hospital, Segovia, Spain
6. Madrid Regional Health Authority, Madrid, Spain
7. Dementia Diagnosis and Treatment Unit, Neurology Department, Bellvitge University Teaching, Bellvitge, Spain
8. Llodio Health Center, Day Medical Center, Oroityu-Getxo-Vizcaya, Spain
9. Psychiatry Department, University of Santiago de Compostela, Santiago de Compostela, Spain
11. Dementia Unit, Hospital Santa Caterina, Institut d'Assistència Sanitària, Salt, Spain
12. Barcelona Hospital, Barcelona, Spain
13. Geriatrics Unit, Virgen del Valle Geriatric Hospital., Toledo, Spain
14. Neurology Service, Cruces Hospital, Day Medical Center, Oroityu-Getxo-Vizcaya, Spain
15. Neurology Department, 12 de Octubre University Teaching Hospital, Madrid, Spain
16. Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain
17. Neurology Department, Bidasoa-Hondarribia Hospital, Guipúzcoa, Spain
文摘
Background This study describes the prevalence of dementia and major dementia subtypes in Spanish elderly. Methods We identified screening surveys, both published and unpublished, in Spanish populations, which fulfilled specific quality criteria and targeted prevalence of dementia in populations aged 70 years and above. Surveys covering 13 geographically different populations were selected (prevalence period: 1990-2008). Authors of original surveys provided methodological details of their studies through a systematic questionnaire and also raw age-specific data. Prevalence data were compared using direct adjustment and logistic regression. Results The reanalyzed study population (aged 70 year and above) was composed of Central and North-Eastern Spanish sub-populations obtained from 9 surveys and totaled 12,232 persons and 1,194 cases of dementia (707 of Alzheimer's disease, 238 of vascular dementia). Results showed high variation in age- and sex-specific prevalence across studies. The reanalyzed prevalence of dementia was significantly higher in women; increased with age, particularly for Alzheimer's disease; and displayed a significant geographical variation among men. Prevalence was lowest in surveys reporting participation below 85%, studies referred to urban-mixed populations and populations diagnosed by psychiatrists. Conclusion Prevalence of dementia and Alzheimer's disease in Central and North-Eastern Spain is higher in females, increases with age, and displays considerable geographic variation that may be method-related. People suffering from dementia and Alzheimer's disease in Spain may approach 600,000 and 400,000 respectively. However, existing studies may not be completely appropriate to infer prevalence of dementia and its subtypes in Spain until surveys in Southern Spain are conducted.