Risk factors for hospital-acquired antimicrobial-resistant infection caused by Acinetobacter baumannii

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• 作者：Darcy Ellis ; Bevin Cohen ; Jianfang Liu…
• 刊名：Antimicrobial Resistance and Infection Control
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：4
• 期：1
• 全文大小：439 KB
• 刊物主题：Medical Microbiology; Drug Resistance; Infectious Diseases;
• 出版者：BioMed Central
• ISSN：2047-2994

文摘

Background Acinetobacter baumannii can cause serious healthcare-associated infections (HAIs) and the incidence is increasing, with many strains now resistant to multiple antibiotic classes. The aims of this study were to examine factors associated with HAIs caused by antimicrobial-resistant as compared with antimicrobial-susceptible strains of A. baumannii and to investigate trends in the incidence of resistance over time. Electronic data from two U.S. hospitals in a large urban healthcare system in over the years 2006–2012 were used for the analysis. Multiple logistic regression was used to explore risk factors for infection with A. baumannii resistant to ampicillin or ampicillin/sulbactam in the bloodstream, urinary tract, and respiratory tract. The Cochran-Armitage trend test was used to explore resistance trends over time.