The occurrence and fate of tetracyclines in two pharmaceutical wastewater treatment plants of Northern China

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• 作者：Jie Hou ; Chong Wang ; Daqing Mao ; Yi Luo
• 关键词：Antibiotics ; Pharmaceutical wastewater treatment plants ; Ultra ; performance liquid chromatography ; Tetracycline removal
• 刊名：Environmental Science and Pollution Research
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：23
• 期：2
• 页码：1722-1731
• 全文大小：665 KB
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• 作者单位：Jie Hou (2)
  Chong Wang (2)
  Daqing Mao (1)
  Yi Luo (2)
  
  2. Key Laboratory of Pollution Processes and Environmental Criteria (Nankai University), College of Environmental Sciences and Engineering, Nankai University, Tianjin, 300071, People’s Republic of China
  1. School of Environmental Science and Engineering, Tianjin University, Tianjin, 300072, People’s Republic of China
  
• 刊物类别：Earth and Environmental Science
• 刊物主题：Environment
  Environment
  Atmospheric Protection, Air Quality Control and Air Pollution
  Waste Water Technology, Water Pollution Control, Water Management and Aquatic Pollution
  Industrial Pollution Prevention
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1614-7499

文摘

Several parameters of the method, solid-phase extraction (SPE)–ultra-performance liquid chromatography (UPLC)–tandem mass spectrometry (MS/MS), were optimized to investigate the presence and partitioning of 18 antibiotics (including sulfonamides, tetracyclines, quinolones, macrolides, and β-lactams) during various processing stages at two typical pharmaceutical wastewater treatment plants (PWWTPs) in northern China. Oxytetracycline (OTC), chlortetracycline (CTC), and tetracycline (TC) were all detected in each stage of both PWWTPs. Antibiotics were largely removed through biological units of both PWWTPs, with removal efficiencies of 62.0 to 78.3 %. Mass balance analyses indicated that degradation (44.8–53.7 % for PWWTP1 and 40.1–59.6 % for PWWTP2) was the major mechanism responsible for the removal of tetracyclines, whereas the contribution of sorption by sludge (12.6–20.0 % for PWWTP1 and 18.7–33.5 % for PWWTP2) was less significant for the investigated pharmaceuticals. Although there was significant removal of tetracyclines through PWWTPs, large amounts of tetracyclines were still discharged through the effluent (up to 32.0 ± 6.0 mg L−1) and dewatered sludge (up to 5,481.1 ± 123.0 mg kg−1), which increased the risk of selecting for antibiotic resistance in the receiving water and soil environments. Keywords Antibiotics Pharmaceutical wastewater treatment plants Ultra-performance liquid chromatography Tetracycline removal