Clinical characteristics and treatment of Herlyn–Werner–Wunderlich syndrome

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• 作者：Jinhui Wang ; Lan Zhu ; Jinghe Lang ; Zhufeng Liu…
• 关键词：Herlyn–Werner–Wunderlich syndrome ; Characteristics ; Classification ; Diagnosis
• 刊名：Archives of Gynecology and Obstetrics
• 出版年：2014
• 出版时间：November 2014
• 年：2014
• 卷：290
• 期：5
• 页码：947-950
• 全文大小：456 KB
• 参考文献：1. Orazi C, Lucchetti MC, Schingo PMS et al (2007) Herlyn–Werner–Wunderlich syndrome: uterus didelphys, blinding hemivagina and ipsilateral renal agenesis. Sonographic and MR findings in 11 cases. Pediatr Radiol 37:657-65 CrossRef
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  11. Haddad B, Barranger E, Paniel B (1999) Blind hemivagina: long-term follow-up and reproductive performance in 42 cases. Hum Reprod 14(8):1962-964 CrossRef
  12. Vercellini P, Daguati R, Somigliana E, Viganò P, Lanzani A, Fedele L (2007) Asymmetric lateral distribution of obstructed hemivagina and renal agenesis in women with uterus didelphys: institutional case series and a systematic literature review. Fertil Steril 87(4):719-24 CrossRef
  
• 作者单位：Jinhui Wang (1)
  Lan Zhu (1)
  Jinghe Lang (1)
  Zhufeng Liu (1)
  Dawei Sun (1)
  Jinhua Leng (1)
  Qingbo Fan (1)
  
  1. Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, 100730, China
  
• ISSN：1432-0711

文摘

Objective To investigate the clinical characteristics and treatment of the Herlyn–Werner–Wunderlich syndrome (HWWS). Methods Sixty-one patients diagnosed with HWWS were retrospectively analyzed. HWWS is categorized into three types in China. Results Age at presentation of all the cases was after menarche. The most common clinical presentations were dysmenorrhea for type I and vaginal discharge for types II and III. Clinical presentations of types II and III may not occur until reproductive age. HWWS occurred on the right in 39/61. Excision of the obstructed vaginal septum was the treatment utilized in this cohort. After surgery, subsequent pregnancies were ipsilateral in 52.9?%. Conclusions Clinical presentation in untreated HWWS suggests the anatomic anomaly. Early recognition and treatment can reduce symptoms. Pregnancies occur in both the affected and unaffected uterus.