Bovine HSD17B8 gene and its relationship with growth and meat quality traits

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• 作者：Yun Ma ; Ningbo Chen ; Fen Li ; Weiwei Fu ; Yapeng Han ; Yanlin Chang…
• 关键词：HSD17B8 ; Polymorphisms ; Growth and meat quality traits ; Native Chinese cattle ; HSD17B8 ; ; /li>
• 刊名：Chinese Science Bulletin
• 出版年：2015
• 出版时间：September 2015
• 年：2015
• 卷：60
• 期：18
• 页码：1617-1621
• 全文大小：380 KB
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• 作者单位：Yun Ma (1)
  Ningbo Chen (1)
  Fen Li (1)
  Weiwei Fu (1)
  Yapeng Han (1)
  Yanlin Chang (1)
  Xiangxiang Jiang (1)
  Junya Li (2)
  Yueyu Bai (3)
  Xuxin Tan (4)
  
  1. College of Life Sciences, Xinyang Normal University, Xinyang, 464000, China
  2. Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, 100094, China
  3. Henan Institute of Animal Health Supervision, Zhengzhou, 450008, China
  4. Henan Center of Animal Products Quality Monitoring and Test, Zhengzhou, 450008, China
  
• 刊物主题：Science, general; Life Sciences, general; Physics, general; Chemistry/Food Science, general; Earth Sciences, general; Engineering, general;
• 出版者：Springer Berlin Heidelberg
• ISSN：1861-9541

文摘

17 β-Hydroxysteroid dehydrogenase type 8 (HSD17B8) is an important regulator of lipid and steroid metabolism. In the present study, we aimed to assess the effects of HSD17B8 on growth and meat quality traits in cattle. Transcription profile analysis showed that HSD17B8 was primarily expressed in the salpinx, liver, and testis. Meanwhile, we identified three SNPs (SNP1: intron 1-A91G; SNP2: exon 1-A90G; and SNP3: intron 8-A86G) of the bovine HSD17B8 gene and investigated its haplotype frequencies and linkage disequilibrium. The detected SNPs were found associated with growth traits (body weight, body length, height at withers, heart girth, hip width, and average daily gain) in native cattle populations (Nanyang and Jiaxian) as well as the meat quality traits (Warner–Bratzler shear force, rib area, dressing percentage, carcass weight, and backfat thickness) in commercial breeds (Angus, Hereford, Limousin, Luxi, Simmental, and Jinnan). Our results provided evidence that polymorphisms in the HSD17B8 gene were associated with growth traits and meat quality traits. Moreover, our findings might be used for marker-assisted selection in beef cattle breeding program. Keywords HSD17B8 Polymorphisms Growth and meat quality traits Native Chinese cattle