One-pot synthesis of 6-bromo-4,4-dimethylthiochroman

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• 作者：Shaodong Zhou (1)
  Zutai Liao (2)
  Jixin Yuan (2)
  Chao Qian (1)
  Xinzhi Chen (1)
  
• 关键词：One ; pot synthesis ; 6 ; Bromo ; 4 ; 4 ; dimethylthiochroman ; Byproduct utilization ; Heterocyclic ; 1 ; Bromo ; 3 ; methylbut ; 2 ; ene
• 刊名：Research on Chemical Intermediates
• 出版年：2013
• 出版时间：November 2013
• 年：2013
• 卷：39
• 期：9
• 页码：4121-4125
• 全文大小：263KB
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• 作者单位：Shaodong Zhou (1)
  Zutai Liao (2)
  Jixin Yuan (2)
  Chao Qian (1)
  Xinzhi Chen (1)
  
  1. State Key Laboratory of Chemical Engineering, Department of Chemical and Biological Engineering, Zhejiang University, Hangzhou, 310027, China
  2. Jiangxi Renming Pharmaceutical Chemicals Ltd., Jiujiang, 100011, China
  
• ISSN：1568-5675

文摘

One-pot synthesis of 6-bromo-4,4-dimethylthiochroman from bromobenzene is reported. The crucial connection between the three steps is that the byproducts in the first two steps are used as the catalyst in the third step. Compared with the previous route, this approach is of low consumption and low pollution.