Evaluation of Mucosal Damage and Recovery in the Gastrointestinal Tract of Rats by a Penetration Enhancer

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• 作者：Yogeeta Narkar ; Ronald Burnette ; Reiner Bleher ; Ralph Albrecht ; Angki Kandela and Joseph R. Robinson
• 关键词：absorption enhancement ; mucosal damage ; mucosal recovery ; oral absorption ; penetration enhancers
• 刊名：Pharmaceutical Research
• 出版年：2008
• 出版时间：January, 2008
• 年：2008
• 卷：25
• 期：1
• 页码：25-38
• 全文大小：817.8 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Pharmacology and Toxicology
  Pharmacy
  Biochemistry
  Medical Law
  Biomedical Engineering
  
• 出版者：Springer Netherlands
• ISSN：1573-904X

文摘

Purpose To evaluate absorption barrier recovery in the gastrointestinal tract after treatment with a penetration enhancer by using a poorly absorbed marker and correlate results with morphological recovery.