Glycemic control among patients in China with type 2 diabetes mellitus receiving oral drugs or injectables
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- 作者：Li-Nong Ji (31)
Ju-Ming Lu (32)
Xiao-Hui Guo (33)
Wen-Ying Yang (34)
Jian-Ping Weng (25)
Wei-Ping Jia (26)
Da-Jin Zou (27)
Zhi-Guang Zhou (28)
De-Min Yu (29)
Jie Liu (30)
Zhong-Yan Shan (31)
Yu-Zhi Yang (32)
Ren-Ming Hu (33)
Da-Long Zhu (34)
Li-Yong Yang (25)
Li Chen (26)
Zhi-Gang Zhao (27)
Qi-Fu Li (28)
Hao-Ming Tian (29)
Qiu-He Ji (30)
Jing Liu (31)
Jia-Pu Ge (32)
Li-Xin Shi (33)
Yan-Cheng Xu (34) - 关键词：China ; GLP ; 1 receptor agonists ; HbA1c ; Insulin ; Oral antidiabetes drugs (OADs) ; Type 2 diabetes mellitus
- 刊名：BMC Public Health
- 出版年：2013
- 出版时间：December 2013
- 年：2013
- 卷：13
- 期：1
- 全文大小：181KB
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19. The pre-publication history for this paper can be accessed here:http://www.biomedcentral.com/1471-2458/13/602/prepub - 作者单位：Li-Nong Ji (31)
Ju-Ming Lu (32)
Xiao-Hui Guo (33)
Wen-Ying Yang (34)
Jian-Ping Weng (25)
Wei-Ping Jia (26)
Da-Jin Zou (27)
Zhi-Guang Zhou (28)
De-Min Yu (29)
Jie Liu (30)
Zhong-Yan Shan (31)
Yu-Zhi Yang (32)
Ren-Ming Hu (33)
Da-Long Zhu (34)
Li-Yong Yang (25)
Li Chen (26)
Zhi-Gang Zhao (27)
Qi-Fu Li (28)
Hao-Ming Tian (29)
Qiu-He Ji (30)
Jing Liu (31)
Jia-Pu Ge (32)
Li-Xin Shi (33)
Yan-Cheng Xu (34)
31. Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China
32. Department of Endocrinology, Xinjiang Uigur Autonomous Region People’s Hospital, Urumqi, China
33. Department of Endocrinology, Affiliated Hospital of Guiyang Medical College, Guiyang, China
34. Department of Endocrinology, Zhongnan Hospital of Wuhan University, Wuhan, China
25. Department of Endocrinology, First Affiliated Hospital of Fujian Medical University, Fuzhou, China
26. Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China
27. Department of Endocrinology, Henan Provincial People’s Hospital, Zhengzhou, China
28. Department of Endocrinology, First Affiliated Hospital of Chongqing Medical University, Chongqing, China
29. Department of Endocrinology, West China Hospital, Sichuan University, Chengdu, China
30. Department of Endocrinology, Xijing Hospital, Fourth Military Medical University, Xi’an, China - ISSN：1471-2458
文摘
Background The prevalence of type 2 diabetes mellitus (T2DM) is increasing rapidly among Chinese adults, and limited data are available on T2DM management and the status of glycemic control in China. We assessed the efficacy of oral antidiabetes drugs (OADs), glucagon-like peptide-1 (GLP-1) receptor agonists, and insulin for treatment of T2DM across multiple regions in China. Methods This was a multicenter, cross-sectional survey of outpatients conducted in 606 hospitals across China. Data from all the patients were collected between April and June, 2011. Results A total of 238,639 patients were included in the survey. Eligible patients were treated with either OADs alone (n=157,212 [65.88%]), OADs plus insulin (n=80,973 [33.93%]), or OADs plus GLP-1 receptor agonists (n=454 [0.19%]). The OAD monotherapy, OAD + insulin, and OAD + GLP-1 receptor agonist groups had mean glycosylated hemoglobin (HbA1c) levels (±SD) of 7.67% (±1.58%), 8.21% (±1.91%), and 7.80% (±1.76%), respectively. Among those three groups, 34.63%, 26.21%, and 36.12% met the goal of HbA1c <7.0%, respectively. Mean HbA1c and achievement of A1c <7.0% was related to the duration of T2DM. Conclusions Less than one third of the patients had achieved the goal of HbA1c <7.0%. Glycemic control decreased and insulin use increased with the duration of diabetes.