Is Passive Smoking Exposure in Early Life a Risk Factor for Future Cardiovascular Disease?

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• 作者：Henry W. West ; Seana L. Gall ; Markus Juonala…
• 关键词：Pediatric ; Passive smoking ; Cardiovascular disease ; Environmental tobacco smoke ; Review ; Atherosclerosis ; Childhood ; Cardiovascular
• 刊名：Current Cardiovascular Risk Reports
• 出版年：2015
• 出版时间：July 2015
• 年：2015
• 卷：9
• 期：9
• 全文大小：983 KB
• 参考文献：Papers of particular interest, published recently, have been highlighted as -Of importance ?-Of major importance1.Schonherr E. Contribution to the statistical and clinical features of lung tumours (in German). Z Krebsforsch. 1928;27:436-0.View Article
  2.English JP, Willius FA, Berkson J. Tobacco and coronary disease. JAMA. 1940;115:1327-.View Article
  3.Smoking NRCUCoP. Environmental tobacco smoke: measuring exposures and assessing health effects (1986). 2015.
  4.Lightwood JM, Glantz SA. Declines in acute myocardial infarction after smoke-free laws and individual risk attributable to secondhand smoke. Circulation. 2009;120:1373-.PubMed Central PubMed View Article
  5.-/div>Tan CE, Glantz SA. Association between smoke-free legislation and hospitalizations for cardiac, cerebrovascular, and respiratory diseases: a meta-analysis. Circulation. 2012;126:2177-3. A meta-analysis of 45 studies revealed comprehensive smoke-free legislation was associated with significantly lower rates of hospital admissions and deaths for coronary events, cerebrovascular accidents, respiratory disease and other heart disease. The difference in risk following comprehensive smoke-free laws does not change with longer follow-up and more comprehensive laws were associated with larger changes in risk.
  6.Glantz SA, Parmley WW. Passive smoking and heart disease. Epidemiology, physiology, and biochemistry. Circulation. 1991;83:1-2.PubMed View Article
  7.Frankel S, Elwood P, Sweetnam P, Yarnell J, Smith GD. Birthweight, adult risk factors and incident coronary heart disease: the Caerphilly Study. Pub Health. 1996;110:139-3.
  8.Magnussen CG, Smith KJ, Juonala M. What the long term cohort studies that began in childhood have taught us about the origins of coronary heart disease. Curr Cardiovasc Risk Rep. 2014;8:373.View Article
  9.?-/div>Gall S, Huynh QL, Magnussen CG, Juonala M, Viikari JS, Kahonen M, et al. Exposure to parental smoking in childhood or adolescence is associated with increased carotid intima-media thickness in young adults: evidence from the cardiovascular risk in young Finns study and the childhood determinants of adult health study. Eur Heart J. 2014;35:2484-1. Children exposed to parental smoking, confirmed by serum cotinine, were significantly more likely to have carotid plaque in adulthood as opposed to those not exposed. Children of parents that maintained good smoking hygiene, by smoking in a way that did not expose their children, were significantly less likely to have developed carotid artery plaque in adulthood.
  10.Geerts CC, Bots ML, Grobbee DE, Uiterwaal CS. Parental smoking and vascular damage in young adult offspring: is early life exposure critical? The atherosclerosis risk in young adults study. Arterioscler Thromb Vasc Biol. 2008;28:2296-02.
  11.?-/div>West HW, Juonala M, Gall SL, Kahonen M, Laitinen T, Taittonen L, et al. Exposure to parental smoking in childhood is associated with increased risk of carotid atherosclerotic plaque in adulthood: the cardiovascular risk in young Finns study. Circulation. 2015;131:1239-6. Children exposed to parental smoking, confirmed by serum cotinine, were significantly more likely to have carotid plaque in adulthood as opposed to those not exposed. Children of parents that maintained good smoking hygiene, by smoking in a way that did not expose their children, were significantly less likely to have developed carotid artery plaque in adulthood.
  12.?-/div>Juonala M, Magnussen CG, Venn A, Gall S, K?h?nen M, Laitinen T, et al. Parental smoking in childhood and brachial artery flow-mediated dilatation in young adults: the cardiovascular risk in young Finns study and the childhood determinants of adult health study. Arterioscler Thromb Vasc Biol. 2012;32:1024-1. Evidence from two major longitudinal cohorts that children exposed to parental smoking in childhood have significantly attenuated brachial artery flow-mediated dilatation, an important marker of endothelial function, in adulthood.
  13.Kvalvik LG, Nilsen RM, Skjaerven R, Vollset SE, Midttun O, Ueland PM, et al. Self-reported smoking status and plasma cotinine concentrations among pregnant women in the Norwegian Mother and Child Cohort Study. Pediatr Res. 2012;72:101-.PubMed Central PubMed View Article
  14.Perez-Rios M, Schiaffino A, Lopez MJ, Nebot M, Galan I, Fu M, et al. Questionnaire-based second-hand smoke assessment in adults. Eur J Pub Health. 2013;23:763-.View Article
  15.Gaffney KF, Molloy SB, Maradiegue AH. Questionnaires for the measurement of infant environmental tobacco smoke exposure: a systematic review. J Nurs Meas. 2003;11:225-9.PubMed View Article
  16.Benowitz NL. Biomarkers of environmental tobacco smoke exposure. Environ Health Perspect. 1999;107 Suppl 2:349-5.PubMed Central PubMed View Article
  17.Jaakkola MS, Jaakkola JJ. Assessment of exposure to environmental tobacco smoke. Eur Respir J. 1997;10:2384-7.PubMed View Article
  18.Wo
• 作者单位：Henry W. West (1)
  Seana L. Gall (1)
  Markus Juonala (2) (3) (4)
  Costan G. Magnussen (1) (4)
  
  1. Menzies Institute for Medical Research, University of Tasmania, Private Bag 23, Hobart, 7001, TAS, Australia
  2. Department of Medicine, University of Turku and Division of Medicine, Turku University Hospital, Turku, Finland
  3. Murdoch Childrens Research Institute, Parkville, Australia
  4. Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland
  
• 刊物主题：Cardiology;
• 出版者：Springer US
• ISSN：1932-9563

文摘

Thanks to the foresight of researchers in the 1970s and 1980s in establishing large cohorts of children to investigate the origins of cardiovascular disease (CVD), we now have the ability to understand the impact childhood smoking exposure, among other pediatric exposures, has on later-life cardiovascular (CV) health. The age of the participants in these large prospective cohorts is still prohibitive in that researchers can only consider pre-clinical markers of CV pathology. Despite this, cohorts from multiple countries have reported consistent findings concerning the adverse CV impact childhood passive smoking exposure is having decades later. Fortunately, we now have sufficient evidence as to the exact mechanisms through which tobacco smoke causes CVD. With a large proportion of the world’s children exposed to passive smoking daily, especially in the as-yet unstudied developing world, but with very few living in jurisdictions with effective and enforced protective legislation, the time for public health action is now.