Preserving Inversion Phylogeny Reconstruction
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  • 作者:Matthias Bernt (21)
    Kun-Mao Chao (22)
    Jyun-Wei Kao (22)
    Martin Middendorf (21)
    Eric Tannier (23)
  • 刊名:Lecture Notes in Computer Science
  • 出版年:2012
  • 出版时间:2012
  • 年:2012
  • 卷:7534
  • 期:1
  • 页码:14-29
  • 全文大小:275KB
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  • 作者单位:Matthias Bernt (21)
    Kun-Mao Chao (22)
    Jyun-Wei Kao (22)
    Martin Middendorf (21)
    Eric Tannier (23)

    21. Parallel Computing and Complex Systems Group, Institute of Computer Science, University Leipzig, Germany
    22. Department of Computer Science and Information Engineering, National Taiwan University, Taiwan
    23. INRIA Rh?ne-Alpes; UMR CNRS 5558 “Biométrie et Biologie évolutive- Université de Lyon 1, Villeurbanne, France
文摘
Tractability results are rare in the comparison of gene orders for more than two genomes. Here we present a linear-time algorithm for the small parsimony problem (inferring ancestral genomes given a phylogeny on an arbitrary number of genomes) in the case gene orders are permutations, that evolve by inversions not breaking common gene intervals, and these intervals are organised in a linear structure. We present two examples where this allows to reconstruct the ancestral gene orders in phylogenies of several γ-Proteobacteria species and Burkholderia strains, respectively. We prove in addition that the large parsimony problem (where the phylogeny is output) remains NP-complete.

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