Silica nanocapsules for redox-responsive delivery
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- 作者：Johannes Fickert (1)
David Schaeffel (1)
Kaloian Koynov (1)
Katharina Landfester (1)
Daniel Crespy (1) - 关键词：Encapsulation ; Miniemulsion ; Nanocapsules ; Nanoparticles ; Redox ; responsive
- 刊名：Colloid & Polymer Science
- 出版年：2014
- 出版时间：January 2014
- 年：2014
- 卷：292
- 期：1
- 页码：251-255
- 全文大小：1,728 KB
- 作者单位：Johannes Fickert (1)
David Schaeffel (1)
Kaloian Koynov (1)
Katharina Landfester (1)
Daniel Crespy (1)
1. Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany - ISSN：1435-1536
文摘
Redox-responsive silica nanocapsules with a hydrophobic liquid core were synthesized by reactive templating of miniemulsion droplets with functional alkoxysilanes. Tetrasulfide bridges were successfully introduced into the inorganic shell and were found to be accessible for chemical reactions as shown by 31P-NMR spectroscopy. Indeed, the tetrasulfide groups could be reduced to yield thiol groups. A subsequent increase of permeability of the silica shell was observed upon reduction of the tetrasulfide groups.