First report of Babesia gibsoni in Central America and survey for vector-borne infections in dogs from Nicaragua

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• 作者：Lanjing Wei (28) (29)
  Patrick Kelly (30)
  Kate Ackerson (30)
  Jilei Zhang (28) (29)
  Heba S El-Mahallawy (28) (31)
  Bernhard Kaltenboeck (32)
  Chengming Wang (28) (29)
  
  28. Yangzhou University College of Veterinary Medicine ; Yangzhou ; Jiangsu ; P. R. China
  29. Jiangsu Co-innovation Center for the Prevention and Control of Important Animal Infectious Diseases and Zoonoses ; Yangzhou ; Jiangsu ; P. R. China
  30. Ross University School of Veterinary Medicine ; St. Kitts and Nevis ; Basseterre
  31. Faculty of Veterinary Medicine ; Suez Canal University ; Ismailia ; Egypt
  32. Auburn University College of Veterinary Medicine ; Auburn ; Al ; USA
  
• 关键词：Nicaragua ; Rickettsia felis ; Babesia gibsoni/vogeli ; Hepatozoon canis ; Anaplasma platys ; Ehrlichia canis ; Coxiella burnetii ; Dirofilaria immitis
• 刊名：Parasites & Vectors
• 出版年：2014
• 出版时间：December 2014
• 年：2014
• 卷：7
• 期：1
• 全文大小：220 KB
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• 刊物主题：Parasitology; Infectious Diseases; Tropical Medicine; Entomology;
• 出版者：BioMed Central
• ISSN：1756-3305

文摘

Background Although many vector-borne diseases are important causes of morbidity and mortality in dogs in tropical areas and potential zoonoses, there is little information on these conditions in Central America. Methods Seven qPCRs for vector-borne pathogens were performed on a Roche LightCycler PCR Instrument to investigate their prevalence in a convenience sample of whole blood samples from apparently healthy dogs in Nicaragua. Also, a qPCR targeting the canine hydroxymethylbilane synthase (HMBS) gene was used as an endogenous internal control and verified the quality and quantity of DNA in the samples was appropriate for the study. Results We found DNA of Rickettsia felis (5%), Babesia spp. (26%), Hepatozoon canis (51%), Anaplasma platys (13%) and Ehrlichia canis (56%) in the 39 dogs studied. The qPCRs for Coxiella burnetii and Dirofilaria immitis were negative. Of the 30 (80%) dogs that were positive by qPCR, 12 (31%) were positive for one agent, 11 (28%) for two, 3 (8%) for three, and 4 (10%) for four agents. Conclusions This is the first report of B. gibsoni in dogs from Central America and the first recording of vector-borne agents in dogs from Nicaragua. Dogs in Nicaragua are commonly infected with a variety of vector-borne pathogens, some of which may also infect people.