Long-Term Efficacy of Arthroscopic Debridement on Knee Osteoarthritis in Patients with Kashin–Beck Disease

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• 作者：Ming Ling ; Zhengming Sun ; Zhi Yi ; Yanhai Chang…
• 关键词：Kashin–Beck disease ; Knee osteoarthritis ; Arthroscopic debridement ; Kellgren–Lawrence classification ; Lysholm scores
• 刊名：Cell Biochemistry and Biophysics
• 出版年：2015
• 出版时间：September 2015
• 年：2015
• 卷：73
• 期：1
• 页码：125-128
• 全文大小：462 KB
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• 作者单位：Ming Ling (1)
  Zhengming Sun (1)
  Zhi Yi (1)
  Yanhai Chang (1)
  Shizhang Liu (1)
  Guang Yang (2)
  Xin Tian (1)
  Xianghui Dong (1)
  
  1. Department of Orthopaedics of the Shaanxi Provincial People’s Hospital, Xi’an, 710068, Shaanxi, China
  2. Vascular Biology Center, Georgia Health Sciences University, Augusta, GA, 30912-2500, USA
  
• 刊物主题：Biochemistry, general; Pharmacology/Toxicology; Biotechnology; Cell Biology; Biophysics and Biological Physics;
• 出版者：Springer US
• ISSN：1559-0283

文摘

Kashin–Beck Disease (KBD) is a chronic and degenerative joint disease with decreased health conditions causing major functional limitations and disability. In this study, we investigated the long-term clinical outcomes of arthroscopic debridement for knee osteoarthritis in KBD patients with Kellgren–Lawrence I–III classification. 31 KBD patients underwent arthroscopic debridement and 24 of them were followed up 8?years after the surgery. The Lysholm scores, femorotibial angle (FTA), and joint space angle (JSA) of the knees were assessed and compared preoperatively and postoperatively to evaluate the clinic outcome. Our results showed that the Lysholm scores, but not the FTA or JSA, of these patients were significantly improved 8?years after the therapy, suggesting that arthroscopic surgery has long-term efficacy in KBD patients with Kellgren–Lawrence I–III classification.