Future developments in biosensors for field-ready Zika virus diagnostics

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• 作者：Ariana M. Nicolini ; Katherine E. McCracken…
• 关键词：Zika ; Flaviviruses ; Biosensors ; RT ; PCR ; LAMP ; Immunoassays
• 刊名：Journal of Biological Engineering
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：11
• 期：1
• 全文大小：1132KB
• 刊物类别：Engineering
• 刊物主题：Biomedical Engineering; Biotechnology; Biological Techniques; Nucleic Acid Chemistry; Applied Microbiology; Environmental Engineering/Biotechnology;
• 出版者：BioMed Central
• ISSN：1754-1611
• 卷排序：11

文摘

Since early reports of the recent Zika virus outbreak in May 2015, much has been learned and discussed regarding Zika virus infection and transmission. However, many opportunities still remain for translating these findings into field-ready sensors and diagnostics. In this brief review, we discuss current diagnostic methods, consider the prospects of translating other flavivirus biosensors directly to Zika virus sensing, and look toward the future developments needed for high-sensitivity and high-specificity biosensors to come.