Biochemical view on: Precocious markers of cardiovascular risk and vascular damage in apparently healthy women with previous gestational diabetes
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- 作者：Huseyin Kayadibi (1)
Erdim Sertoglu (2)
Metin Uyanik (3)
1. Adana Military Hospital ; Medical Biochemistry Laboratory ; Adana ; 01150 ; Turkey
2. Ankara Mevki Military Hospital ; Anittepe Dispensary ; Biochemistry Laboratory ; Ankara ; Turkey
3. Corlu Military Hospital ; Biochemistry Laboratory ; Tekirdag ; Turkey - 关键词：Gestational diabetes ; Cardiovascular risk ; Microangiopathy ; Endothelial dysfunction ; Homocysteine
- 刊名：Diabetology and Metabolic Syndrome
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：7
- 期：1
- 全文大小：274 KB
- 参考文献：1. Zajdenverg, L, Rodacki, M, Faria, JP, Pires, ML, Oliveira, JE, Halfoun, VL (2014) Precocious markers of cardiovascular risk and vascular damage in apparently healthy women with previous gestational diabetes. Diabetol Metab Syndr. 6: pp. 63 CrossRef
2. Idzior-Walu艣, B, Cyganek, K, Sztefko, K, Seghieri, G, Breschi, MC, Walu艣-Miarka, M (2008) Total plasma homocysteine correlates in women with gestational diabetes. Arch Gynecol Obstet 278: pp. 309-13 CrossRef
3. Katre, P, Bhat, D, Lubree, H, Otiv, S, Joshi, S, Joglekar, C (2010) Vitamin B12 and folic acid supplementation and plasma total homocysteine concentrations in pregnant Indian women with low B12 and high folate status. Asia Pac J Clin Nutr 19: pp. 335-43 - 刊物主题：Diabetes; Metabolic Diseases; Endocrinology;
- 出版者：BioMed Central
- ISSN：1758-5996
文摘
Women diagnosed with gestational diabetes mellitus have an increased risk of developing diabetes mellitus, which is a known risk factor for cardiovascular disease and insulin resistance. In the recently published article by Zajdenverg et al., they aimed to identify endothelial dysfunction and cardiovascular risk factors in women with previous gestational diabetes mellitus. However, authors did not evaluate the role of total homocysteine, which has important effects for endothelial dysfunction. Vitamin B12 and folic acid are important vitamins since their deficiency may lead to the probable microvascular abnormalities by increasing the tHcy, which is an independent risk factor for endothelial dysfunction.