Profibrotic role of WNT10A via TGF-β signaling in idiopathic pulmonary fibrosis

详细信息    查看全文

• 作者：Keishi Oda ; Kazuhiro Yatera ; Hiroto Izumi ; Hiroshi Ishimoto…
• 关键词：Acute exacerbation ; Idiopathic pulmonary fibrosis ; Autopsy ; Diffuse alveolar damage ; WNT/β ; catenin pathway ; Fibroblast
• 刊名：Respiratory Research
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：17
• 期：1
• 全文大小：3,403 KB
• 刊物主题：Pneumology/Respiratory System;
• 出版者：BioMed Central
• ISSN：1465-9921

文摘

Background WNT/β-catenin signaling plays an important role in the pathogenesis of idiopathic pulmonary fibrosis (IPF); however, the role of WNT10A via transforming growth factor (TGF)-β signaling remains unclear.