Central motor drive and perception of effort during fatigue in multiple sclerosis

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• 作者：Gary W. Thickbroom ; Paul Sacco ; Allan G. Kermode ; Sarah A. Archer ; Michelle L. Byrnes ; Andrew Guilfoyle and Frank L. Mastaglia
• 关键词：multiple sclerosis ; fatigue ; perceived exertion ; TMS
• 刊名：Journal of Neurology
• 出版年：2006
• 出版时间：August, 2006
• 年：2006
• 卷：253
• 期：8
• 页码：1048-1053
• 全文大小：123 KB

文摘

Objective To determine if task performance and fatiguability during repeated low-level contractions of an intrinsic hand muscle differ in a group of MS subjects compared with a control group, and what central changes accompany the development of fatigue and the period of recovery, whether these measures are related to subjective ratings of fatigue or perception of effort.