Objective and subjective image quality of primary and recurrent squamous cell carcinoma on head and neck low-tube-voltage 80-kVp computed tomography
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  • 作者:Jan-Erik Scholtz ; Moritz Kaup ; Johannes Kraft ; Eva-Maria N?ske…
  • 关键词:Head and neck ; Squamous cell carcinoma ; Low dose ; Low tube voltage ; Dual ; energy computed tomography
  • 刊名:Neuroradiology
  • 出版年:2015
  • 出版时间:June 2015
  • 年:2015
  • 卷:57
  • 期:6
  • 页码:645-651
  • 全文大小:1,147 KB
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  • 作者单位:Jan-Erik Scholtz (1)
    Moritz Kaup (1)
    Johannes Kraft (1)
    Eva-Maria N?ske (1)
    Friedrich Scheerer (2)
    Boris Schulz (1)
    Iris Burck (1)
    Jens Wagenblast (3)
    J. Matthias Kerl (1)
    Ralf W. Bauer (1)
    Thomas Lehnert (1)
    Thomas J. Vogl (1)
    Julian L. Wichmann (1)

    1. Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany
    2. Department of Cranio-Maxillofacial and Plastic Facial Surgery, University Hospital Frankfurt, Frankfurt, Germany
    3. Department of Otolaryngology, Head and Neck Surgery, University Hospital Frankfurt, Frankfurt, Germany
  • 刊物类别:Medicine
  • 刊物主题:Medicine & Public Health
    Neuroradiology
    Imaging and Radiology
    Neurology
    Neurosurgery
    Neurosciences
  • 出版者:Springer Berlin / Heidelberg
  • ISSN:1432-1920
文摘
Introduction To investigate low-tube-voltage 80-kVp computed tomography (CT) of head and neck primary and recurrent squamous cell carcinoma (SCC) regarding objective and subjective image quality. Methods We retrospectively evaluated 65 patients (47 male, 18 female; mean age: 62.1?years) who underwent head and neck dual-energy CT (DECT) due to biopsy-proven primary (n--0) or recurrent (n--5) SCC. Eighty peak kilovoltage and standard blended 120-kVp images were compared. Attenuation and noise of malignancy and various soft tissue structures were measured. Tumor signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Subjective image quality was rated by three reviewers using 5-point grading scales regarding overall image quality, lesion delineation, image sharpness, and image noise. Radiation dose was assessed as CT dose index volume (CTDIvol). Interobserver agreement was calculated using intraclass correlation coefficient (ICC). Results Mean tumor attenuation (153.8 Hounsfield unit (HU) vs. 97.1 HU), SNR (10.7 vs. 8.3), CNR (8.1 vs. 4.8), and subjective tumor delineation (score, 4.46 vs. 4.13) were significantly increased (all P-lt;-.001) with 80-kVp acquisition compared to standard blended 120-kVp images. Noise of all measured structures was increased in 80-kVp acquisition (P-lt;-.001). Overall interobserver agreement was good (ICC, 0.86; 95?% confidence intervals: 0.82-.89). CTDIvol was reduced by 48.7?% with 80-kVp acquisition compared to standard DECT (4.85?±-.51 vs. 9.94?±-.81?mGy?cm, P-lt;-.001). Conclusions Head and neck CT with low-tube-voltage 80-kVp acquisition provides increased tumor delineation, SNR, and CNR for CT imaging of primary and recurrent SCC compared to standard 120-kVp acquisition with an accompanying significant reduction of radiation exposure.

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