On the modeling of the motion of a transcription bubble under constant torque

详细信息    查看全文

• 作者：A. A. Grinevich ; L. V. Yakushevich
• 关键词：DNA dynamics modeling ; transcription bubble ; torsion moment ; kinks
• 刊名：Biophysics
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：61
• 期：4
• 页码：539-546
• 全文大小：1,131 KB
• 刊物主题：Biophysics and Biological Physics;
• 出版者：Springer US
• ISSN：1555-6654
• 卷排序：61

文摘

The motion of a transcription bubble under constant torque is investigated. The motion of the bubble was modeled by a modified sine-Gordon equation. Numerical solutions of this equation (kinks) were found. Trajectories of the kink motion in homogeneous and inhomogeneous sequences were calculated for different model values of the torque M_τ and the initial velocity v₀. It was shown that a change in the torsion moment M_τ has a significant impact on the character of the kink trajectory. At the same time, a change in the initial kink velocity v₀ in a rather wide range of values does not affect the character of the kink trajectory.