Future therapies for ARDS
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  • 作者:Gerard F. Curley (1) (2)
    John G. Laffey (1) (2)

    1. Department of Anesthesia
    ; Critical Illness and Injury Research Centre ; Keenan Research Centre for Biomedical Science ; The Li Ka Shing Knowledge Institute ; St. Michael鈥檚 Hospital ; 30 Bond Street ; Toronto ; ON ; M5B 1W8 ; Canada
    2. Department of Anesthesia
    ; University of Toronto ; Toronto ; Canada
  • 刊名:Intensive Care Medicine
  • 出版年:2015
  • 出版时间:February 2015
  • 年:2015
  • 卷:41
  • 期:2
  • 页码:322-326
  • 全文大小:156 KB
  • 参考文献:1. Tonelli AR, Zein J, Adams J, Ioannidis JP (2014) Effects of interventions on survival in acute respiratory distress syndrome: an umbrella review of 159 published randomized trials and 29 meta-analyses. Intensive Care Med 40(6):769鈥?87 CrossRef
    2. Erlich JM, Talmor DS, Cartin-Ceba R, Gajic O, Kor DJ (2011) Prehospitalization antiplatelet therapy is associated with a reduced incidence of acute lung injury: a population-based cohort study. Chest 139:289鈥?95 CrossRef
    3. Kor DJ, Talmor DS, Banner-Goodspeed VM, Carter RE, Hinds R, Park PK, Gajic O, Gong MN, US Critical Illness and Injury Trials Group: Lung Injury Prevention with Aspirin Study Group (USCIITG: LIPS-A) (2012) Lung injury prevention with aspirin (LIPS-A): a protocol for a multicentre randomised clinical trial in medical patients at high risk of acute lung injury. BMJ Open:2(5)
    4. Craig TR, Duffy MJ, Shyamsundar M, McDowell C, O鈥橩ane CM, Elborn JS, McAuley DF (2011) A randomized clinical trial of hydroxymethylglutaryl-coenzyme a reductase inhibition for acute lung injury (The HARP Study). Am J Respir Crit Care Med 183:620鈥?26 CrossRef
    5. McAuley DF, Laffey JG, O鈥橩ane CM, Perkins GD, Mullan B, Trinder TJ, Johnston P, Hopkins PA, Johnston AJ, McDowell C, McNally C, HARP-2 Investigators, Irish Critical Care Trials Group (2014) Simvastatin in the acute respiratory distress syndrome. N Engl J Med 371:1695鈥?703 CrossRef
    6. National Heart L, Blood Institute ACTN, Truwit JD, Bernard GR, Steingrub J, Matthay MA, Liu KD, Albertson TE, Brower RG, Shanholtz C, Rock P, Douglas IS, de Boisblanc BP, Hough CL, Hite RD, Thompson BT (2014) Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med 370:2191鈥?200 CrossRef
    7. Dixon B, Schultz MJ, Smith R, Fink JB, Santamaria JD, Campbell DJ (2010) Nebulized heparin is associated with fewer days of mechanical ventilation in critically ill patients: a randomized controlled trial. Crit Care 14:R180 CrossRef
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    9. Bertok S, Wilson MR, Morley PJ, de Wildt R, Bayliffe A, Takata M (2012) Selective inhibition of intra-alveolar p55 TNF receptor attenuates ventilator-induced lung injury. Thorax 67:244鈥?51 CrossRef
    10. Proudfoot AG, O鈥橩ane CM, Bayliffe A, Serone AP, Bareille P, Smith SP, Brown V, Wright TJ, Chen Y, Wilson R, Cordy JC, Morley PJ, Elborn S, Hind M, Chilvers ER, Griffiths MJ, Summers C, McAuley DF (2014) A novel TNFR1-targeting domain antibody attenuates pulmonary inflammation in a human model of lung injury, via actions on the lung micro-vascular endothelium. Am J Respir Crit Care Med 189:A6589
    11. Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, Yang P, Sarao R, Wada T, Leong-Poi H, Crackower MA, Fukamizu A, Hui CC, Hein L, Uhlig S, Slutsky AS, Jiang C, Penninger JM (2005) Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature 436:112鈥?16 CrossRef
    12. Kuba K, Imai Y, Rao S, Gao H, Guo F, Guan B, Huan Y, Yang P, Zhang Y, Deng W, Bao L, Zhang B, Liu G, Wang Z, Chappell M, Liu Y, Zheng D, Leibbrandt A, Wada T, Slutsky AS, Liu D, Qin C, Jiang C, Penninger JM (2005) A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med 11:875鈥?79 CrossRef
    13. Adamzik M, Frey U, Sixt S, Knemeyer L, Beiderlinden M, Peters J, Siffert W (2007) ACE I/D but not AGT (-6)A/G polymorphism is a risk factor for mortality in ARDS. Eur Respir J 29:482鈥?88 CrossRef
    14. Temmesfeld-Wollbruck B, Hocke AC, Suttorp N, Hippenstiel S (2007) Adrenomedullin and endothelial barrier function. Thromb Haemost 98:944鈥?51
    15. Shyamsundar M, McAuley DF, Ingram RJ, Gibson DS, O鈥橩ane D, McKeown ST, Edwards A, Taggart C, Elborn JS, Calfee CS, Matthay MA, O鈥橩ane CM (2014) Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung injury. Am J Respir Crit Care Med 189:1520鈥?529 CrossRef
    16. Curley GF, Scott JA, Laffey JG (2014) Therapeutic potential and mechanisms of action of mesenchymal stromal cells for acute respiratory distress syndrome. Curr Stem Cell Res Ther 9:319鈥?29 CrossRef
    17. Curley GF, Ansari B, Hayes M, Devaney J, Masterson C, Ryan A, Barry F, O鈥橞rien T, Toole DO, Laffey JG (2013) Effects of intratracheal mesenchymal stromal cell therapy during recovery and resolution after ventilator-induced lung injury. Anesthesiology 118:924鈥?32 CrossRef
    18. Curley GF, Hayes M, Ansari B, Shaw G, Ryan A, Barry F, O鈥橞rien T, O鈥橳oole D, Laffey JG (2012) Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat. Thorax 67:496鈥?01 CrossRef
    19. Zheng G, Huang L, Tong H, Shu Q, Hu Y, Ge M, Deng K, Zhang L, Zou B, Cheng B, Xu J (2014) Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study. Respir Res 15:39 CrossRef
  • 刊物主题:Intensive / Critical Care Medicine; Anesthesiology; Emergency Medicine; Pneumology/Respiratory System; Pain Medicine; Pediatrics;
  • 出版者:Springer Berlin Heidelberg
  • ISSN:1432-1238
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